Skip to main content

Table 2 Comparison between pre and post-treatment according to different clinical and laboratory parameters

From: B-type natriuretic peptide (BNP) in HCV-positive Egyptian patients: the impact of HCV eradication on plasma BNP levels

 

Pre (n = 89)

Post (n = 89)

Test of sig.

P

BMI (kg/m2)

 18.5–24.9

22(24.7%)

18(20.2%)

MH = 2.828

0.157

 25.0–29.9

67(75.3%)

71(79.8%)

 Mean ± SD.

26.9 ± 2

26.8 ± 2.1

Z = 0.763

0.446

 Median (min.–max.)

27.1(22.9–29.9)

27.1(20.7–29.4)

Total bilirubin

 Mean ± SD.

0.9 ± 0.2

1.2 ± 0.2

Z = 6.922*

< 0.001*

 Median (nin.–max.)

0.8 (0.6–1.6)

1.2 (0.7–1.6)

INR

 Mean ± SD.

1.1 ± 0.1

1.1 ± 0.1

Z = 1.068

0.286

 Median (min.–max.)

1 (1–1.4)

1 (1–1.3)

ALT

 Mean ± SD.

49.3 ± 28.6

36.4 ± 7.6

Z = 7.237*

< 0.001*

 Median (min.–max.)

45 (14–199)

36 (16–50)

AST

 Mean ± SD.

44.7 ± 18

34.3 ± 7.3

Z = 7.003*

< 0.001*

 Median (min.–max.)

43 (15–100)

34 (17–60)

Creatinine

 Mean ± SD.

0.9 ± 0.2

1.0 ± 0.2

Z = 1.866

0.062

 Median (min.–max.)

0.9 (0.6–1.4)

0.9 (0.6–1.6)

FIB4

 < 1.45

43 (48.3%)

51 (57.3%)

MH = 28.0*

0.003*

 1.45–3.25

42 (47.2%)

38 (42.7%)

 > 3.25

4 (4.5%)

0 (0%)

 Mean ± SD.

1.7 ± 0.9

1.6 ± 0.6

Z = 2.199*

0.028*

 Median (min.–max.)

1.5 (0.6–5.2)

1.4 (0.7–3.0)

APRI

 < 0.5

46 (51.7%)

52 (58.4%)

MH = 37.0*

0.033*

 0.5 –1.5

39 (43.8%)

37 (41.6%)

 > 1.5

4 (4.5%)

0 (0%)

 Mean ± SD.

0.6 ± 0.4

0.5 ± 0.2

Z = 4.464*

< 0.001*

 Median (min.–max.)

0.5 (0.1–1.9)

0.4 (0.1–0.9)

HB

 Mean ± SD.

13.5 ± 1.4

12.6 ± 1.2

t = 7.009*

< 0.001*

 Median (min.–max.)

13.7 (9–16)

12.6 (10–15.0)

Platelet count

 Mean ± SD.

209 ± 65.3

199.3 ± 61.9

Z = 1.592

0.111

 Median (min.–max.)

202 (83–478)

198 (101–417)

WBCs

 Mean ± SD.

6.7 ± 1.8

6.1 ± 1.4

Z = 1.802

0.072

 Median (min.–max.)

6.3 (3.6–10.3)

5.9(4.5–9.3)

BNP level TTT

 Mean ± SD.

21.4 ± 23.9

24.4 ± 25.6

Z=1.536

0.124

 Median (min.–max.)

16 (0.7–165.5)

18.4 (8.7–180.7)

Delta BNP level

3 ± 37.5

  
  1. MH marginal homogeneity test, t paired t test, Z Wilcoxon signed ranks test, SD standard deviation, p p value for comparing between pre and post
  2. BMI body mass index, INR international normalized ratio, ALT alanine aminotransferase, AST aspartate aminotransferase, HB hemoglobin concentration, WBCs white blood cells, APRI score aspartate aminotransferase-to-platelet ratio index score, BNP B-type natriuretic peptide, delta BNP BNP after – BNP before treatment
  3. *Statistically significant at p < 0.05