Table 8 C/D ratio in correlation with different genotype of donor when recipient genotype is CT or TT (Mann–Whitney test)

1st wk

 C/D ratio

Median (IQR)

115.65(55.55–150.75)

138.7(113.5–160.3)

−0.775

0.439

NS

Range

22.5–350

72–294.4

 Dose

Median (IQR)

0.05(0.04–0.06)

0.04(0.03–0.05)

−0.589

0.556

NS

Range

0.01–0.06

0.02–0.09

 Trough level

Median (IQR)

4.18(1.95–4.95)

5.6(4.2–6.7)

−1.678

0.093

NS

Range

0.9–5.8

2.6–7.9

2nd wk

 C/D

Median (IQR)

100.25(65.1–126)

121.2(92.5–176.4)

−0.711

0.477

NS

Range

33.75–187.5

54.7–740

 Dose

Median (IQR)

0.06(0.04–0.08)

0.07(0.04–0.1)

−0.393

0.694

NS

Range

0.04–0.1

0.01–1.5

 Trough level

Median (IQR)

5.35(3.5–7.75)

5.65(5–6.3)

−0.065

0.948

NS

Range

2.7–9.6

2.7–7.4

3rd wk

 C/D

Median (IQR)

76.35(63.92–124)

125.75(98.6–196)

−0.904

0.366

NS

Range

58–310

57.3–200.3

 Dose

Median (IQR)

0.07(0.05–0.07)

0.05(0.04–0.08)

−0.327

0.744

NS

Range

0.03–0.1

0.03–0.1

 Trough level

Median (IQR)

5.35(4–7.7)

6.3(5.5–7.8)

−1.033

0.302

NS

Range

2.9–9.3

5.2–15

4th wk

 C/D

Median (IQR)

128.6(119.65–191)

114.45(91.4–133)

−1.291

0.197

NS

Range

110–250

72.32–326.4

 Dose

Median (IQR)

0.04(0.02–0.06)

0.07(0.05–0.07)

−1.899

0.058

NS

Range

0.02–0.07

0.04–0.09

 Trough level

Median (IQR)

5.15(4.75–6.55)

7.5(6.1–8.5)

−2.200

0.028

S

Range

2.2–8.4

5.46–14.5

2 months

 Dose

Median (IQR)

0.04(0.03–0.08)

0.05(0.03–0.1)

−0.575

0.565

NS

Range

0.02–0.08

0.03–0.1

 Trough level

Median (IQR)

6.7(6.4–8.1)

6.2(5.9–6.8)

−0.568

0.570

NS

Range

2.2–8.4

5.5–14.6

 C/D

Median (IQR)

140(94–202)

113(59–226)

−0.081

0.935

NS

Range

82.5–213

55–486

3 months

 Dose

Median (IQR)

0.04(0.03–0.06)

0.05(0.04–0.07)

−0.818

0.414

NS

Range

0.01–0.07

0.02–0.1

 Trough level

Median (IQR)

5.8(1.5–8.2)

5.8(4.5–6.9)

−0.082

0.935

NS

Range

1.4–9.1

4.5–7

 C/D

Median (IQR)

140(70–150)

112.5(99–127)

−0.407

0.684

NS

Range

47–150

58–205