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Table 6 Relation of ABCB1 genotype and C/D ratio, tacrolimus dose, and trough levels among the donor group 2 months and 3 months post transplantation (Mann–Whitney test)

From: Clinical utility of ABCB1 single nucleotide polymorphism on tacrolimus dose requirements in Egyptian liver transplant patients

ABCB1 CC CT+TT U test P-value Sig.
2nd month      
Dose Median (IQR) 0.05(0.04–0.08) 0.08(0.04–0.1) −0.812 0.417 NS
Range 0.02–0.1 0.03–0.1
Trough level Median (IQR) 6.65(5.9–8.1) 6.05(5.1–9.85) −0.222 0.824 NS
Range 2.2–10.6 3.8–14.6
C/D Median (IQR) 108(82.5–167) 86(54.5–184.5) −0.355 0.722 NS
Range 49–213 47–486
3rd month      
Dose Median (IQR) 0.05(0.03–0.06) 0.08(0.05–0.1) −1.878 0.060 NS
Range 0.01–0.07 0.02–0.1
Trough level Median (IQR) 5.4(2.1–8.2) 5.35(4.5–6.95) −0.089 0.929 NS
Range 1.4–9.1 3.2–7.4
C/D Median (IQR) 142.5(71–150) 90.5(59.5–119.75) −1.422 0.155 NS
Range 47–225 32–205
  1. P-value >0.05, non-significant (NS); P-value <0.05, significant (S); P-value< 0.01, highly significant (HS)