Table 2 Follow-up for C/D, tacrolimus dose, and tacrolimus concentration among recipients during the first 4 weeks post transplantation (Friedman test)
1st week | 2nd week | 3rd week | 4th week | Test value | P-value | Sig. | ||
|---|---|---|---|---|---|---|---|---|
No. = 25 | No. = 25 | No. = 25 | No. = 25 | |||||
C/D | Median (IQR) | 98.8 (46–140) | 95.2 (66.3–122.4) | 105 (66–131.4) | 117.3 (91.2–134.7) | 1.289 | 0.732 | NS |
Range | 22.5–350 | 33.75–740 | 38.16–310 | 62.1–326.0 | ||||
Dose (mg/kg/day) | Median (IQR) | 0.05 (0.03–0.07) | 0.06 (0.04–0.08) | 0.06 (0.04–0.08) | 0.05 (0.04–0.07) | 4.915 | 0.178 | NS |
Range | 0.01–0.7 | 0.01–4 | 0.02–5.2 | 0.02–4.5 | ||||
Trough level (ng/dl) | Median (IQR) | 4.25 (2.40–5.30) | 5.1 (3.9–6.8) | 5.7 (4.5–6.9) | 5.7 (5–6.5) | 5.331 | 0.004 | HS |
Range | 0.9–7.9 | 2.7–9.6 | 2.9–15 | 1.4–14.5 | ||||