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Table 2 Follow-up for C/D, tacrolimus dose, and tacrolimus concentration among recipients during the first 4 weeks post transplantation (Friedman test)

From: Clinical utility of ABCB1 single nucleotide polymorphism on tacrolimus dose requirements in Egyptian liver transplant patients

  1st week 2nd week 3rd week 4th week Test value P-value Sig.
No. = 25 No. = 25 No. = 25 No. = 25
C/D Median (IQR) 98.8 (46–140) 95.2 (66.3–122.4) 105 (66–131.4) 117.3 (91.2–134.7) 1.289 0.732 NS
Range 22.5–350 33.75–740 38.16–310 62.1–326.0
Dose (mg/kg/day) Median (IQR) 0.05 (0.03–0.07) 0.06 (0.04–0.08) 0.06 (0.04–0.08) 0.05 (0.04–0.07) 4.915 0.178 NS
Range 0.01–0.7 0.01–4 0.02–5.2 0.02–4.5
Trough level (ng/dl) Median (IQR) 4.25 (2.40–5.30) 5.1 (3.9–6.8) 5.7 (4.5–6.9) 5.7 (5–6.5) 5.331 0.004 HS
Range 0.9–7.9 2.7–9.6 2.9–15 1.4–14.5