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Table 9 Adiponectin genotype and polymorphism, CAP, and metabolic parameters in relation to the degree of obesity

From: The association of adiponectin gene polymorphisms with susceptibility and progression of NAFLD in a cohort of Egyptian patients

 

Obese (67), N (%)

Non obese (19), N (%)

P value

Mild (30-34.9), N=38, N (%)

Moderate (35–39.9), N=19, N (%)

Morbid (>40), N=10, N (%)

P value

rs266729 CG

 Yes

44 (65.67)

9 (47.37)

0.18

25 (65.79)

13 (68.42)

4 (40)

0.9

 No

23 (34.33)

10 (52.63)

13 (34.2)

6 (31.58)

6 (60)

 

rs3774261 AG

 Yes

44 (65.67)

11 (57.9)

0.59

24 (63.16)

14 (73.68)

6 (60)

0.67

 No

23 (34.33)

8 (42.1)

14 (36.84)

5 (26.32)

4 (40)

Steatosis

 S1

8 (11.9)

8 (42.1)

0.011

5 (13.16)

3 (15.79)

0 (0)

0.43

 S2

29 (43.3)

6 (31.6)

19 (50)

6 (31.58)

4 (40)

 

 S3

30 (44.8)

5 (26.3)

14 (36.84)

10 (52.63)

6 (60)

 
 

Mean±SD

Mean±SD

 

Mean±SD

Mean±SD

Mean±SD

 

Waist circumference

111 ±10

96 ±8

<0.0001

105 ±7.5

114 ± 8.2

125 ±4.6

<0.0001

BMI

36 ±4.7

27 ±1.9

<0.0001

32 ±1.5

37 ±1.4

45 ±3.6

<0.0001

ALT

44 ± 33

38 ±19

0.97

38 ±33

9–180

30

53 ± 31

18–121

45

47 ±30

8–89

37

0.05

TGS

188 ±105

157 ±82

0.36

167 ±100

230 +118

185 + 83

0.16

Fasting glucose level

98 ±30

95 ±23

0.72

93 ±18

92 ±25

127 ±53

0.0048

AST

41 ±25

35 ±13

0.84

37 ±26

49 ± 23

42 ± 25

0.044