Safety and efficacy of directly acting antivirals (sofosbuvir and daclatasvir) in treatment of chronic HCV in HIV-HCV co-infected Egyptian patients

Egyptian Liver Journal

Table 1 Comparison of liver function tests findings before, after, and 12 weeks after end of treatment

Items	Liver function tests findings (mean ± SD)
Items	Alanine amino transferase	Aspartate amino transferase	Serum albumin	Total bilirubin	αfetoprotein
Before treatment	54.80±39.10	52.20±39.93	4.13±0.38	0.86±0.25	7.13±5.02
End of treatment	30.90±11.91	32.20±10.31	4.06±0.29 0	0.88±0.27	6.76±3.42
SVR at 12 weeks	28.23±10.49	30.28±10.46	4.14±0.24	0.76±0.22	6.75±3.83
F-value	10.815	7.319	0.588	1.175	0.081
P-value	0.0001	0.001	0.557	0.180	0.923
Significance	S	S	NS	NS	NS