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Table 1 Comparison of liver function tests findings before, after, and 12 weeks after end of treatment

From: Safety and efficacy of directly acting antivirals (sofosbuvir and daclatasvir) in treatment of chronic HCV in HIV-HCV co-infected Egyptian patients

Items

Liver function tests findings (mean ± SD)

Alanine amino transferase

Aspartate amino transferase

Serum albumin

Total bilirubin

αfetoprotein

Before treatment

54.80±39.10

52.20±39.93

4.13±0.38

0.86±0.25

7.13±5.02

End of treatment

30.90±11.91

32.20±10.31

4.06±0.29 0

0.88±0.27

6.76±3.42

SVR at 12 weeks

28.23±10.49

30.28±10.46

4.14±0.24

0.76±0.22

6.75±3.83

F-value

10.815

7.319

0.588

1.175

0.081

P-value

0.0001

0.001

0.557

0.180

0.923

Significance

S

S

NS

NS

NS

  1. SD standard deviation, P-value probability, S significant