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Table 1 Comparison of liver function tests findings before, after, and 12 weeks after end of treatment

From: Safety and efficacy of directly acting antivirals (sofosbuvir and daclatasvir) in treatment of chronic HCV in HIV-HCV co-infected Egyptian patients

Items Liver function tests findings (mean ± SD)
Alanine amino transferase Aspartate amino transferase Serum albumin Total bilirubin αfetoprotein
Before treatment 54.80±39.10 52.20±39.93 4.13±0.38 0.86±0.25 7.13±5.02
End of treatment 30.90±11.91 32.20±10.31 4.06±0.29 0 0.88±0.27 6.76±3.42
SVR at 12 weeks 28.23±10.49 30.28±10.46 4.14±0.24 0.76±0.22 6.75±3.83
F-value 10.815 7.319 0.588 1.175 0.081
P-value 0.0001 0.001 0.557 0.180 0.923
Significance S S NS NS NS
  1. SD standard deviation, P-value probability, S significant