Variable | ALT | AST | PLT | Bilirubin | Fib-4 | APRI |
---|---|---|---|---|---|---|
Baseline | 44.86 ± 21.34 | 51.41 ± 22.95 | 195 ± 68 | 0.93 ± 0.40 | 2.42 ± 1.69 | 0.821 ± 0.08 |
4 weeks | 25.19 ± 9.07 | 32.46 ± 11.93 | 196 ± 66 | 1.29 ± 0.69 |  |  |
 Percent of change | − 43.84% | − 36.86% | 0.41% | 38.7% |  |  |
 p value | 0.001* |  0.001* | ns | 0.001* |  |  |
8 weeks | 23.46 ± 9.33 | 27.64 ± 10.91 | 207 ± 74 | 1.26 ± 0.64 |  |  |
 Percent of change | − 47.70% | − 46.23% | 5.80% | 35.48% |  |  |
 p value | 0.001* |  0.001* | ns | 0.001* |  |  |
12 weeks (EOT) | 26.68 ± 7.96 | 29.03 ± 7.14 | 215 ± 52 | 0.98 ± 0.44 |  |  |
 Percent of change | − 40.52% | − 43.54% | 10.11% | 5.37% |  |  |
 p value | 0.001* |  0.001* |  0.05* | ns |  |  |
12 weeks after EOT (SVR 12) | 24.46 ± 7.63 | 29.53 ± 6.61 | 218 ± 64 | 0.77 ± 0.20 | 1.60 ± 0.61 | 0.407 ± 0.08 |
 Percent of change | − 45.47% | − 42.55% | 11.67% | − 17.2% | − 33.88% | − 50.42% |
 p value | 0.001* |  0.001* |  0.05* |  0.001* | 0.001* | 0.027* |