Ascitic calprotectin as a useful marker in the diagnosis of spontaneous bacterial peritonitis in adults

Egyptian Liver Journal

Table 1 Comparison of patients with and without SBP

	None	SBP	P
	n = 40	n = 40	P
Age (years)	54.75 ± 8.19	55.75 ± 7.64	0.574	NS
Males	25 (62.5%)	26 (65%)	0.816	NS
Females	15 (37.5%)	14 (35%)	0.816	NS
HCV	30 (75%)	31 (77.5%)	0.793	NS
HBV	10 (25%)	9 (22.5%)	0.793	NS
CTP B	12 (30%)	4 (10%)	0.025	S
CTP C	28 (70%)	36 (90%)	0.025	S
Total bilirubin (mg/dL)	2.3 (1.28)	4.2 (4.9)	0.001	S
Albumin (mg/dL)	2.25 (1.1)	1.8 (0.8)	0.006	S
AST (U/L)	77.50 (28)	73 (17.25)	0.083	NS
ALT (U/L)	46.00 (26.25)	43 (21.25)	0.146	NS
Hemoglobin (g/dL)	10.10 ± 1.71	10.11 ± 1.14	0.969	NS
WBCs (μL)	4150 (5475)	9800 (4375)	0.001	S
Platelets (μL)	89,000 (22,250)	82,500 (32,750)	0.008	S
INR	1.9 (0.7)	3.4 (1.45)	0.001	S
Creatinine (mg/dL)	1.1 (0.85)	1.65 (1.4)	0.274	NS
CTP	10.5 ± 1.97	12.18 ± 1.74	0.001	S
MELD	19 (8)	26.5 (11)	0.001	S
Ascitic PMN	65 (76.75)	657.5 (652)	0.001	S
Ascitic total protein	0.41 (0.85)	0.8 (0.75)	0.004	S
Ascitic albumin	0.11 (0.35)	0.22 (0.38)	0.025	S
Ascitic glucose	126 (110)	125.5 (116.75)	0.769	NS
Ascitic LDH	20.65 (26.65)	101 (198.25)	0.001	S
Serum NO (μM)	15.5 (8.78)	17 (12.2)	0.357	NS
Ascitic NO (μM)	5.6 (6.4)	6.2 (4.5)	0.739	NS
Serum CRP (mg/dL)	12 (11.5)	49 (66.25)	0.001	S
Serum hsCRP (ng/dL)	23,750 (52,200)	58,000 (0)	0.001	S
Ascitic calprotectin (ng/mL)	1.1 (0.6)	7.57 (6.76)	0.001	S
Ascitic leucocyte esterase +ve	1 (2.5%)	38 (95%)	0.001	S

CTP Child-Pugh, CRP C-reactive protein, hsCRP High sensitivity C-reactive protein, LDH Lactate dehydrogenase, MELD Model for End-Stage Liver Disease, NS Non-statistically significant, NO Nitrous oxide, S Statistically significant, PMN Polymorphonuclear leucocyte count
Data are expressed as mean ± standard deviation for normally distributed data, median (interquartile range) for data that lacks normal distribution and number (percentage) for nominal data.