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Table 2 Comparison between culture-positive and culture-negative SBP patients, regarding serum and AF biomarkers

From: A novel serum index for accurate diagnosis of spontaneous bacterial peritonitis in cirrhotic patients without other infections

 

Culture negative

n = 35

Culture-positive

n = 25

P

ALT (median/IQR, IU/L)

38/15–45

26/15–39

0.413*

AST (median/IQR, IU/L)

44/31–74

48/22–79

0.554*

Serum LDH (mean ± SD, IU/L)

225 ± 46

229 ± 58

0.750

Blood TLC (median/IQR, × 103/mm3)

7.0/4.8–9.0

7.0/4.3–8.6

0.553*

Platelets count (median/IQR, × 103/mm3)

82/66–145

80/68–133

0.887*

ESR (median/IQR, mm/hour)

32/22–36

30/28–35

0.952*

CRP (median/IQR, mg/L)

26/24–28

27/25–30

0.253

PCT (median/IQR, ng/mL)

0.614/0.410–0.649

1.733/1.256–2.500

< 0.001*

PEC index [PCT × (ESR + CRP)] (median/IQR)

36.34/25.22–40.19

101.48/70.79–136.89

< 0.001*

Ascitic fluid albumin (mean ± SD, g/dL)

0.865 ± 0.13

0.889 ± 0.13

0.467

Ascitic fluid glucose (mean ± SD, g/dL)

104 ± 9

93 ± 13

< 0.001

Ascitic fluid LDH (mean ± SD, IU/L)

142 ± 28

177 ± 50

< 0.001

Ascitic fluid PMNL (median/IQR, cell/mm3)

275/260–310

655/463–6700

< 0.001*

  1. SD standard deviation, IQR interquartile range, ALT alanine aminotransferase, AST aspartate aminotransferase, LDH lactate dehydrogenase, TLC total leukocytic count, ESR erythrocyte sedimentation rate, CRP C-reactive protein, PCT procalcitonin, PMNL polymorphonuclear leukocytes
  2. *Mann–Whitney U test