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Table 2 Comparison between culture-positive and culture-negative SBP patients, regarding serum and AF biomarkers

From: A novel serum index for accurate diagnosis of spontaneous bacterial peritonitis in cirrhotic patients without other infections

  Culture negative
n = 35
Culture-positive
n = 25
P
ALT (median/IQR, IU/L) 38/15–45 26/15–39 0.413*
AST (median/IQR, IU/L) 44/31–74 48/22–79 0.554*
Serum LDH (mean ± SD, IU/L) 225 ± 46 229 ± 58 0.750
Blood TLC (median/IQR, × 103/mm3) 7.0/4.8–9.0 7.0/4.3–8.6 0.553*
Platelets count (median/IQR, × 103/mm3) 82/66–145 80/68–133 0.887*
ESR (median/IQR, mm/hour) 32/22–36 30/28–35 0.952*
CRP (median/IQR, mg/L) 26/24–28 27/25–30 0.253
PCT (median/IQR, ng/mL) 0.614/0.410–0.649 1.733/1.256–2.500 < 0.001*
PEC index [PCT × (ESR + CRP)] (median/IQR) 36.34/25.22–40.19 101.48/70.79–136.89 < 0.001*
Ascitic fluid albumin (mean ± SD, g/dL) 0.865 ± 0.13 0.889 ± 0.13 0.467
Ascitic fluid glucose (mean ± SD, g/dL) 104 ± 9 93 ± 13 < 0.001
Ascitic fluid LDH (mean ± SD, IU/L) 142 ± 28 177 ± 50 < 0.001
Ascitic fluid PMNL (median/IQR, cell/mm3) 275/260–310 655/463–6700 < 0.001*
  1. SD standard deviation, IQR interquartile range, ALT alanine aminotransferase, AST aspartate aminotransferase, LDH lactate dehydrogenase, TLC total leukocytic count, ESR erythrocyte sedimentation rate, CRP C-reactive protein, PCT procalcitonin, PMNL polymorphonuclear leukocytes
  2. *Mann–Whitney U test