Table 6 Insulin resistance (assessed by HOMA-IR and QUICKI index) and genotypes of IRS-1 SNP in relation to the degree of liver cirrhosis (assessed by Child–Pugh classification) in group III
Child class A | Child class B | Child class C | Test of sig. | P | |
|---|---|---|---|---|---|
HOMA-IR | |||||
Min.–Max. | 0.80–5.30 | 0.50–2.40 | 0.90–2.40 | F = 3.324 | 0.044 |
Mean ± SD. | 2.267 ± 1.650 | 1.589 ± 0.501 | 1.994 ± 0.448 | ||
QUICKI index | |||||
Min.–Max. | 0.30–0.40 | 0.33–0.43 | 0.33–0.39 | F = 3.444 | 0.040 |
Mean ± SD. | 0.352 ± 0.040 | 0.361 ± 0.022 | 0.342 ± 0.018 | ||
Genotype | |||||
GG | 1 | 18 | 5 | X2 = 8.934 | 0.063 |
GA | 5 | 9 | 12 | ||
AA | 0 | 1 | 1 | ||