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Table 6 Insulin resistance (assessed by HOMA-IR and QUICKI index) and genotypes of IRS-1 SNP in relation to the degree of liver cirrhosis (assessed by Child–Pugh classification) in group III

From: Insulin receptor substrate-1 G972R single nucleotide polymorphism in Egyptian patients with chronic hepatitis C virus infection and type 2 diabetes mellitus

 

Child class A

Child class B

Child class C

Test of sig.

P

HOMA-IR

 Min.–Max.

0.80–5.30

0.50–2.40

0.90–2.40

F = 3.324

0.044

 Mean ± SD.

2.267 ± 1.650

1.589 ± 0.501

1.994 ± 0.448

QUICKI index

 Min.–Max.

0.30–0.40

0.33–0.43

0.33–0.39

F = 3.444

0.040

 Mean ± SD.

0.352 ± 0.040

0.361 ± 0.022

0.342 ± 0.018

Genotype

 GG

1

18

5

X2 = 8.934

0.063

 GA

5

9

12

 AA

0

1

1