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Table 6 Insulin resistance (assessed by HOMA-IR and QUICKI index) and genotypes of IRS-1 SNP in relation to the degree of liver cirrhosis (assessed by Child–Pugh classification) in group III

From: Insulin receptor substrate-1 G972R single nucleotide polymorphism in Egyptian patients with chronic hepatitis C virus infection and type 2 diabetes mellitus

  Child class A Child class B Child class C Test of sig. P
HOMA-IR
Min.–Max. 0.80–5.30 0.50–2.40 0.90–2.40 F = 3.324 0.044
Mean ± SD. 2.267 ± 1.650 1.589 ± 0.501 1.994 ± 0.448
QUICKI index
Min.–Max. 0.30–0.40 0.33–0.43 0.33–0.39 F = 3.444 0.040
Mean ± SD. 0.352 ± 0.040 0.361 ± 0.022 0.342 ± 0.018
Genotype
GG 1 18 5 X2 = 8.934 0.063
GA 5 9 12
AA 0 1 1