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Table 1 Different biochemical data in the studied groups

From: Vitamin D receptor gene polymorphism and hepatocellular carcinoma in chronic hepatitis C patients

  Group A
Control
(n = 34)
Group B
HCC
(n = 34)
Group C
chronic hepatitis (n = 34)
P value
Age 49.3 ± 6.5 53.8 ± 8.3a 50.9 ± 6.9 0.06*
Gender (M/F) 16/18 23/11 17/17 0.182
BMI (kg/ m2) 23.09 ± 0.45 23.19 ± 0.47 23.16 ± 0.49 0.668
Total bilirubin (mg/dl) 0.85 ± 0.17 2.32 ± 1.33a 1.87 ± 1.14b 0.005*
Direct bilirubin (mg/dl) 0.39 ± 0.11 0.81 ± 0.58a 0.97 ± 0.67b 0.032*
ALT (IU/L) 25 ± 3.55 97.79 ± 25.32a 91.41 ± 60.27b < 0.001**
AST (IU/L) 22.67 ± 4.28 77.71 ± 21.53a 93.94 ± 85.15b < 0.001**
Albumin (g/dl) 4.22 ± 0.44 2.82 ± 0.71a 3.06 ± 0.47b < 0.001**
ALP (IU/L) 64.35 ± 11.39 108.97 ± 37.7a 112.38 ± 57.31b < 0.001**
AFP (ng/mL) 6.45 ± 1.63 3599.09 ± 4450.75a 26.13 ± 23.87c < 0.001**
Creatinine (mg/dL) 0.87 ± 0.12 1.04 ± 0.27a 0.94 ± 0.19 0.004*
Urea (mg/dL). 33.85 ± 3.74 31.59 ± 3.89a 33.15 ± 2.87 0.029*
Hemoglobin (g/dL) 12.71 ± 0.76 12.28 ± 1.61a 12.03 ± 1.61b 0.125
Platelets count (× 103 mm3) 222 ± 49.14 134.97 ± 7.13a 130.77 ± 73.72b < 0.001**
INR 1.02 ± 0.04 1.38 ± 0.39a 1.49 ± 0.43b < 0.001**
PT (s) 12.27 ± 0.46 16.68 ± 4.91a 17.89 ± 5.17b < 0.001**
  1. *P < 0.05 is significant
  2. **P < 0.001 is highly significant
  3. aSignificant difference between group A (control) and B(HCC)
  4. bSignificant difference between group A (control) and C(chronic hepatitis)
  5. cSignificant difference between group B (HCC) and C(chronic hepatitis)