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Table 6 Comparison of different IL-18 genotypes alleles in the groups

From: Interleukin-18 polymorphism as a diagnostic tumor marker for hepatocellular carcinoma in patients with hepatitis C-related cirrhosis

IL-18 genotype allele Group Within-group significance
Control group (N = 40) Cirrhosis group (N = 74) HCC group (N = 66)
A 20 (50.0%) 41 (55.4) 36 (54.6) p1 = 0.58
p2 = 0.65
p3 = 0.92
C 20 (50.0%) 33 (44.6) 30 (45.4)
G 39 (97.5) 64 (54.6) 56 (84.8) p1 < 0.001*
p2 = 0.03*
p3 = 0.78
C 1 (2.5) 10 (45.4) 10 (15.2)
  1. This table shows that there is a statistically significant difference in the G allele in the cirrhosis and HCC groups in comparison with the control group (p1 < 0.001 and p2 = 0.03, respectively), and others were less significant
  2. p1 comparison of the control and cirrhosis groups, p2 comparison of control and HCC, p3 comparison of cirrhosis and HCC