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Egyptian Liver Journal

Table 6 Comparison of different IL-18 genotypes alleles in the groups

From: Interleukin-18 polymorphism as a diagnostic tumor marker for hepatocellular carcinoma in patients with hepatitis C-related cirrhosis

IL-18 genotype allele

Group

Within-group significance

Control group (N = 40)

Cirrhosis group (N = 74)

HCC group (N = 66)

A

20 (50.0%)

41 (55.4)

36 (54.6)

p1 = 0.58

p2 = 0.65

p3 = 0.92

C

20 (50.0%)

33 (44.6)

30 (45.4)

G

39 (97.5)

64 (54.6)

56 (84.8)

p1 < 0.001*

p2 = 0.03*

p3 = 0.78

C

1 (2.5)

10 (45.4)

10 (15.2)

  1. This table shows that there is a statistically significant difference in the G allele in the cirrhosis and HCC groups in comparison with the control group (p1 < 0.001 and p2 = 0.03, respectively), and others were less significant
  2. p1 comparison of the control and cirrhosis groups, p2 comparison of control and HCC, p3 comparison of cirrhosis and HCC
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