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Table 4 Statistical comparison between pre-treatment and post-treatment parameters in glycemic non-improved patients

From: Effect of eradication of HCV infection by direct-acting antivirals in diabetic HCV-infected patients as regards glycemic control

 

Pre-treatment (no = 53)

Post-treatment (no = 53)

P value

Hemoglobin (g/dL)a

12.98 ± 1.34

12.25 ± 1.44

0.001

Leukocytes (× 103/μL cells)a

6.53 ± 1.67

6.98 ± 1.72

0.038

Platelets (× 103/μL cells)a

223.57 ± 50.09

228.91 ± 51.77

0.150

Albumin (g/dL)a

4.25 ± 0.42

4.28 ± 0.39

0.249

Bilirubin, total (mg/dL)a

0.81 ± 0.15

0.67 ± 0.16

0.001

INRa

1.29 ± 1.36

1.07 ± 0.06

0.253

AST (IU/L)a

50.65 ± 24.36

22.38 ± 7.83

0.001

ALT (IU/L)a

55.71 ± 27.48

23.87 ± 9.43

0.001

Creatinine (mg/dL)a

1.02 ± 0.86

0.93 ± 0.18

0.404

HbA1c (%)a

8.17 ± 0.58

7.91 ± 0.79

0.001

AFP (ng/mL)a

7.08 ± 5.01

6.43 ± 4.09

0.012

FIB-4b scorea

1.89 ± 0.85

1.38 ± 0.47

0.001

  1. aMean ± SD. Glycemic improved group: ≥ 1% reduction of baseline HbA1c levels at SVR. Non-glycemic improved group: < 1% reduction of baseline HbA1c levels at SVR
  2. AFP Alpha-fetoprotein, ALT Alanine transaminase, AST Aspartate transaminase, bFIB-4 score = [age 3AST]/[platelets 3 ALT1/2], INR international normalized ratio, HbA1c glycated hemoglobin