Table 4 Mean platelet count in diffrent weeks of treatment
From: Impact of different anti-HCV regimens on platelet count during treatment in Egyptian patients
Platelet count (×103 cell/mm3) | All patients mean ± SD, mean PLT, % drop to baseline | Group 1 Triple (n 56), mean PLT, % drop to baseline | Group 2 SOF/RBV (n 55) mean PLT, % drop to baseline | Group 3 SIM/SOF (n 57) mean PLT, % drop to baseline | p value (among three groups) |
|---|---|---|---|---|---|
Baseline PLT | 108.85 ± 39.74 | 136.89 ± 31.70 | 77.18 ± 18.01 | 111.84 ± 40.35 | < 0.001 |
Week 1 | 89.72 ± 27.93 18% | 86.89 ± 23.62 37% | 75.89 ± 14.09 3% | 105.84 ± 33.56 6% | < 0.001 |
Week 2 | 90.87 ± 33.90 17% | 99.50 ± 36.89 28% | 72.58 ± 12.30 7% | 100.04 ± 38.18 10% | < 0.001 |
Week 3 | 87.65 ± 25.17 20% | 96.05 ± 28.4 30% | 76.07 ± 13.23 2% | 90.58 ± 26.68 19% | < 0.001 |
Week 4 | 88.46 ± 32.08 19% | 101.71 ± 44.1 26% | 77.55 ± 14.26 0% | 85.98 ± 25.69 24% | < 0.001 |
Week 8 | 94.98 ± 37.93 13% | 97.05 ± 39.27 29% | 87.73 ± 30.95 | 99.93 ± 42.08 11% | 0.312 |
Week 12 | 99.46 ± 41.84 9% | 102.86 ± 46.37 25% | 90.16 ± 30.62 | 105.31 ± 45.67 6% | 0.17 |