Table 4 Tumour characteristics of HCC cases according to IL-10 polymorphism
Total, n = 73 | Genotype | Test of significance | |||
|---|---|---|---|---|---|
TT/AA | CT/CA | CC/CC | |||
Portal vein | |||||
Thrombosed | 10 | 10 (34.5) | 0 (0.0) | 0 (0.0) | MC P < 0.001* |
Patent | 63 | 19 (65.5) | 21 (100.0) | 23 (100.0) | |
Spleen | |||||
Splenectomy | 2 | 0 (0.0) | 2 (9.5) | 0 (0.0) | MC P = 0.154 |
Mild | 26 | 7 (24.1) | 11 (52.4) | 8 (34.8) | |
Moderate | 39 | 19 (65.5) | 8 (38.1) | 12 (52.2) | |
Marked | 6 | 2 (6.9) | 2 (9.5) | 2 (8.7) | |
Ascites | |||||
Negative | 62 | 20 (69.0) | 19 (90.5) | 23 (100.0) | MC P = 0.006* |
Positive | 11 | 9 (31.0) | 2 (9.5) | 0 (0.0) | |
Lymph node | |||||
Negative | 64 | 23 (79.3) | 21 (100.0) | 20 (87.0) | MC P = 0.089 |
Positive | 9 | 6 (20.7) | 0 (0.0) | 3 (13.0) | |
BCLC | |||||
A | 11 | 0 (0.0) | 7 (33.3) | 4 (17.4) | MC P < 0.001* |
B | 24 | 3 (10.3) | 7 (33.3) | 14 (60.9) | |
C | 24 | 13 (44.8) | 7 (33.3) | 4 (17.4) | |
D | 14 | 13 (44.8) | 0 (0.0) | 1 (4.3) | |
Site of lesion | |||||
Right lobe | 25 | 10 (34.5) | 6 (28.6) | 9 (39.1) | MC P = 0.929 |
Left lobe | 12 | 5 (17.2) | 3 (14.3) | 4 (17.4) | |
Multifocal | 36 | 14 (48.3) | 12 (57.1) | 10 (43.5) | |
AGI | |||||
A | 22 | 2 (6.9) | 8 (38.1) | 12 (52.2) | MC P < 0.001* |
B | 23 | 6 (20.7) | 9 (42.9) | 8 (34.8) | |
C | 28 | 21 (72.4) | 4 (19.0) | 3 (13.0) | |