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Table 1 Demographic, laboratory, and metabolic parameters of patients with the NASH and control groups

From: Association of vitamin D supplementation with serum leptin and metabolic parameters in Egyptian patients with non-alcoholic steatohepatitis: a prospective study

Characteristics

NASH

Control

t value

p value

Significance

Age (years)

35.2 ± 7.0

34.3 ± 8.2

0.5412

0.5899

NS

Male

21 (52.5%)

24 (60%)

   

Female

19 (47.5%)

16 (40%)

   

Weight (kg)

106.3 ± 15.6

82.2 ± 8.2

8.6455

< 0.0001

HS

Height (meter)

1.7 ± 0.08

1.7 ± 0.1

0.0156

0.9876

NS

BMI (kg/m2)

35.7 ± 5.7

27.5 ± 2.5

8.3947

< 0.0001

HS

DBP (mmHg)

94.3 ± 11.9

79.3 ± 11.2

5.8312

< 0.0001

HS

Hepatomegaly

20 (50%)

2 (5%)

   

HbA1c (%)

8.0 ± 2.4

5.2 ± 0.6

7.2677

< 0.0001

HS

Hemoglobin (gm/dL)

13.5 ± 1.5

13.2 ± 1.3

0.8487

0.3986

NS

Platelet (× 103/μL)

288.5 ± 114.9

322.1 ± 118.7

1.2836

0.2031

NS

FBS (mg/dL)

165.6 ± 62.0

101.7 ± 22.9

6.1141

< 0.0001

HS

Fasting insulin (μU/ml)

24.2 ± 3.0

17.0 ± 2.3

12.1379

< 0.0001

HS

HOMA-IR

1.8 ± 0.7

0.8 ± 0.2

8.8731

< 0.0001

HS

Creatinine (mg/dL)

0.9 ± 0.2

0.9 ± 0.3

2.6252

0.8252

NS

ALT (U/L)

78.2 ± 36.7

29.9 ± 8.3

8.1260

< 0.0001

HS

AST (U/L)

108.6 ± 85.6

25.5 ± 7.5

6.1183

< 0.0001

HS

Albumin (gm/dL)

3.8 ± 0.8

4.6 ± 0.6

4.7217

< 0.0001

HS

NAFLD fibrosis score

− 0.78 ± 0.9

− 3.0 ± 1.6

7.8602

< 0.0001

HS

TCHOL (mg/dL)

233.0 ± 40.9

201.9 ± 41.53

3.3796

0.0011

HS

LDL (mg/dL)

117.5 ± 41.6

95.35 ± 31.1

2.7022

0.0084

HS

HDL (mg/dL)

48.5 ± 7.59

64.58 ± 8.2

9.1398

< 0.0001

HS

Triglycerides (mg/dL)

229.7 ± 62.1

142.9 ± 36.3

7.6224

< 0.0001

HS

ALP (mg/dL)

70.4 ± 7.3

58.2 ± 6.9

7.6925

< 0.0001

HS

GGT (U/L)

43.3 ± 24.5

25.1 ± 7.1

4.5140

< 0.0001

HS

Total bilirubin (mg/dL)

1.1 ± 0.4

1.1 ± 1.1

0.2240

0.8234

NS

Vitamin D (ng/ml)

15.6 ± 6.6

21.0 ± 6.5

3.7323

0.0004

HS

Leptin (ng/ml)

35.9 ± 28.4

10.1 ± 1.8

5.7407

< 0.0001

HS