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Table 1 Demographic, laboratory, and metabolic parameters of patients with the NASH and control groups

From: Association of vitamin D supplementation with serum leptin and metabolic parameters in Egyptian patients with non-alcoholic steatohepatitis: a prospective study

Characteristics NASH Control t value p value Significance
Age (years) 35.2 ± 7.0 34.3 ± 8.2 0.5412 0.5899 NS
Male 21 (52.5%) 24 (60%)    
Female 19 (47.5%) 16 (40%)    
Weight (kg) 106.3 ± 15.6 82.2 ± 8.2 8.6455 < 0.0001 HS
Height (meter) 1.7 ± 0.08 1.7 ± 0.1 0.0156 0.9876 NS
BMI (kg/m2) 35.7 ± 5.7 27.5 ± 2.5 8.3947 < 0.0001 HS
DBP (mmHg) 94.3 ± 11.9 79.3 ± 11.2 5.8312 < 0.0001 HS
Hepatomegaly 20 (50%) 2 (5%)    
HbA1c (%) 8.0 ± 2.4 5.2 ± 0.6 7.2677 < 0.0001 HS
Hemoglobin (gm/dL) 13.5 ± 1.5 13.2 ± 1.3 0.8487 0.3986 NS
Platelet (× 103/μL) 288.5 ± 114.9 322.1 ± 118.7 1.2836 0.2031 NS
FBS (mg/dL) 165.6 ± 62.0 101.7 ± 22.9 6.1141 < 0.0001 HS
Fasting insulin (μU/ml) 24.2 ± 3.0 17.0 ± 2.3 12.1379 < 0.0001 HS
HOMA-IR 1.8 ± 0.7 0.8 ± 0.2 8.8731 < 0.0001 HS
Creatinine (mg/dL) 0.9 ± 0.2 0.9 ± 0.3 2.6252 0.8252 NS
ALT (U/L) 78.2 ± 36.7 29.9 ± 8.3 8.1260 < 0.0001 HS
AST (U/L) 108.6 ± 85.6 25.5 ± 7.5 6.1183 < 0.0001 HS
Albumin (gm/dL) 3.8 ± 0.8 4.6 ± 0.6 4.7217 < 0.0001 HS
NAFLD fibrosis score − 0.78 ± 0.9 − 3.0 ± 1.6 7.8602 < 0.0001 HS
TCHOL (mg/dL) 233.0 ± 40.9 201.9 ± 41.53 3.3796 0.0011 HS
LDL (mg/dL) 117.5 ± 41.6 95.35 ± 31.1 2.7022 0.0084 HS
HDL (mg/dL) 48.5 ± 7.59 64.58 ± 8.2 9.1398 < 0.0001 HS
Triglycerides (mg/dL) 229.7 ± 62.1 142.9 ± 36.3 7.6224 < 0.0001 HS
ALP (mg/dL) 70.4 ± 7.3 58.2 ± 6.9 7.6925 < 0.0001 HS
GGT (U/L) 43.3 ± 24.5 25.1 ± 7.1 4.5140 < 0.0001 HS
Total bilirubin (mg/dL) 1.1 ± 0.4 1.1 ± 1.1 0.2240 0.8234 NS
Vitamin D (ng/ml) 15.6 ± 6.6 21.0 ± 6.5 3.7323 0.0004 HS
Leptin (ng/ml) 35.9 ± 28.4 10.1 ± 1.8 5.7407 < 0.0001 HS