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Table 1 Baseline characteristic data of the studied patients

From: Effect of sofosbuvir plus daclatasvir on virological response and liver function tests as a line of treatment for HCV related cirrhosis (a prospective cohort study)

Variables

Studied patients (N = 240)

Age

 

 Mean ± SD

52.9 ± 8.8 years

Gender

 

 Male

143 (59.6%)

 Female

97 (40.4%)

Previous HCV treatment

 

 Treatment naïve

240 (100%)

 Treatment experienced

0 (0.0%)

Viral load, IU/L

 

 Median (IQR)

5455685 (496040–18102824)

Fibroscan value, kPa

 

 Mean ± SD

25.8 ± 4.5

Serum ALT, IU/L

 

 Median (IQR)

62.5 (40.0–98.5)

Serum albumin, g/dL

 

 Mean ± SD

3.54 ± 0.46

Total bilirubin, mg/dL

 

 Mean ± SD

1.42 ± 0.60

INR

 

 Mean ± SD

1.19 ± 0.22

Child-Pugh score

 

 Mean ± SD

7.3 ± 1.5

Serum creatinine, mg/dL

 

 Mean ± SD

1.1 ± 0.3

AFP, ng/mL

 

 Median (IQR)

21.0 (18.0–30.0)

Platelet count, × 109 per liter

 

 Mean ± SD

131.5 ± 37.1

Treatment regimen

 

 Sofosbuvir + daclatasvir

240 (100.0%)

 Other regimens

0 (0.0%)

Serious adverse effects

0 (0.0%)

Discontinuation of treatment

0 (0.0%)

  1. Data are presented as mean ± SD, median (IQR), or number (%)
  2. SD standard deviation, IQR interquartile range, HCV hepatitis C virus, ALT alanine aminotransferase, AFP alpha-fetoprotein, INR international normalization ratio