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Table 6 Agreement (sensitivity, specificity) for different parameters to predict patients with stage IV from stage II + III

From: Role of circulating miRNA-17-3P as a potential diagnostic biomarker for sporadic colon cancer in Egyptian cohort

 AUCp95% CICutoffSensitivity (CI)Specificity (CI)PPV (CI)NPV (CI)
L.LU.L
miRNA0.713*0.010*0.5660.859> 6.8768.0 (46.5–85.1)72.0 (50.6–87.9)70.8 (52.56–89.0)69.2 (51.4–86.9)
CA19.90.682*0.028*0.5310.832> 1284.0 (69.6–98.4)52.0 (32.4–71.6)63.6 (47.2–80.1)76.5 (56.3–96.6)
CEA0.5260.7490.3600.693≤ 2.752.0 (32.4–71.6)56 (36.54–75.5)54.2 (34.23–74.1)53.8 (34.7–73.0)
  1. AUC area under a curve, p value probability value, CI confidence intervals, NPV negative predictive value, PPV positive predictive value
  2. *Statistically significant at p ≤ 0.05