Table 6 Agreement (sensitivity, specificity) for different parameters to predict patients with stage IV from stage II + III
| Â | AUC | p | 95% CI | Cutoff | Sensitivity (CI) | Specificity (CI) | PPV (CI) | NPV (CI) | |
|---|---|---|---|---|---|---|---|---|---|
L.L | U.L | ||||||||
miRNA | 0.713* | 0.010* | 0.566 | 0.859 | > 6.87 | 68.0 (46.5–85.1) | 72.0 (50.6–87.9) | 70.8 (52.56–89.0) | 69.2 (51.4–86.9) |
CA19.9 | 0.682* | 0.028* | 0.531 | 0.832 | > 12 | 84.0 (69.6–98.4) | 52.0 (32.4–71.6) | 63.6 (47.2–80.1) | 76.5 (56.3–96.6) |
CEA | 0.526 | 0.749 | 0.360 | 0.693 | ≤ 2.7 | 52.0 (32.4–71.6) | 56 (36.54–75.5) | 54.2 (34.23–74.1) | 53.8 (34.7–73.0) |