Skip to main content

Table 3 Agreement (sensitivity, specificity) for AFP, OPN, and ANXA2 to diagnose HCC

From: Role of annexin A2 and osteopontin for early diagnosis of hepatocellular carcinoma in hepatitis C virus patients

  AUC P 95% C.I. Cutoff Sensitivity Specificity PPV NPV Accuracy
AFP (ng/ml) 0.818* < 0.001* 0.719–0.916 > 6# 77.50 82.50 81.6 78.6 80.0
OPN (ng/ml) 0.739* < 0.001* 0.621–0.857 > 13.2# 65.0 90.0 86.7 72.0 77.50
ANXA2 (ng/ml) 0.927* < 0.001* 0.872–0.982 > 10.1# 85.0 85.0 85.0 85.0 85.0
  1. AUC area under a curve, CI confidence intervals, NPV negative predictive value, PPV positive predictive value
  2. *Statistically significant at p ≤ 0.05
  3. #Cut off was done by using Youden index