Table 3 Univariate and multivariate analysis: comparison between thrombophilic parameters in HCC patients with and without thrombotic complications
Variables | Univariate | Multivariate | ||||
|---|---|---|---|---|---|---|
ORs | 95% CIs | P value | ORs | 95% CIs | P value | |
PT (s) | 13.12 | 4.64–18.12 | 0.00 | 6.78 | 2.65–10.89 | 0.00 |
Prothrombin conc.% | 1.54 | 0.94–3.11 | 0.18 | – | – | – |
TT (s) | 1.92 | 0.63–3.81 | 0.142 | – | – | – |
Fbg (g/l) | 10.37 | 4.64–18.44 | 0.00 | 3.97 | 2.17–12.34 | 0.00 |
APTT (s) | 2.27 | 0.87–3.44 | 0.085 | 2.33 | 0.71–7.75 | 0.11 |
Protein C deficiency (%) | 11.32 | 3.45–18.44 | 0.00 | 4.81 | 3.11–10.82 | 0.00 |
Protein S deficiency (%) | 10.45 | 4.31–16.85 | 0.00 | 4.32 | 2.98–11.42 | 0.00 |
Antithrombin deficiency (%) | 8.98 | 4.21–18.32 | 0.00 | 2.71 | 0.64–1.74 | 0.068 |
Increased lipoprotein (a) (mg/l) | 3.88 | 3.13–8.69 | < .0001 | 2.784 | 2.23–5.36 | 0.01 |
Hyperhomocysteinemia (μmol/l) | 6.24 | 3.41–19.24 | 0.000 | 7.06 | 2.15–14.6 | 0.000 |
APCR | 2.11 | 1.03–3.07 | 0.03 | 2.53 | 1.12–4.71 | 0.04 |
FVL mutation | 7.76 | 3.76–17.19 | < .0001 | 6.12 | 2.25–15.41 | 0.0003 |