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Table 1 Demographic data and parameters of the studied groups

From: Thrombophilia in hepatocellular carcinoma

Variables

 

Control group

Cirrhotic patients

HCC patients

P value

Post hoc analysis

Number

 

45

70

70

  

Age

 

54.8 ± 7.19

55 ± 6.43

56.87 ± 6.26

0.148*

 

Sex (male/female)

 

23/22

40/30

42/28

χ2 0.6413

 

Etiology

      

 Chronic hepatitis C

 

45

48

χ2 0.8369

 

 Chronic hepatitis B

 

9

10

 

 Non-alcoholic steatohepatitis

 

8

5

 

 Autoimmune hepatitis

 

6

4

 

 Cryptogenic

 

2

3

 

Child-Pugh’s score

      

 Child A

 

3

4

χ2 0.224

 

 Child B

 

20

29

 

 Child C

 

47

37

 

MELD score

 

15 (4–25)

19 (10–40)

< 0.001**

 

AFP (ng/ml)

 

6 (2–15)

8 (2–20)

1700 (500–3500)

0.000***

P1 = 0.97

P2 < 0.001

P3 < 0.001

  1. Values are expressed as the mean ± standard deviation (SD) while values of MELD score and AFP are given as the median and interquartile range (IQR)
  2. Significant difference (P value < 0.05)
  3. χ2 chi-square test, P1 control group vs cirrhotic patients, P2 control group vs HCC patients, P3 cirrhotic patients vs HCC patients, MELD model for end-stage liver disease, AFP α-fetoprotein
  4. *ANOVA test
  5. **Mann-Whitney U test
  6. ***Kruskal-Wallis test