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  1. Chronic hepatitis C virus (HCV) infection represents a major health-related burden in Egypt. HCV is considered as a major cardiovascular risk factor. BNP (B-type natriuretic peptide) has been determined as a c...

    Authors: Ali Nada, Aliaa Sabry, Naglaa S. Elabd, Azza M. Abdu Allah, Nada Elnaidany and Mohamed Abbasy
    Citation: Egyptian Liver Journal 2021 11:62
  2. Around 25% of the world population was affected by the metabolic-related fatty liver disorder. Hepatic steatosis is frequently observed in conjunction with hypertension, obesity comorbidities, and diabetes. We...

    Authors: Asmaa Ali, Mona Hasan, Shaimaa Hamed and Amir Elhamy
    Citation: Egyptian Liver Journal 2021 11:61
  3. Non-alcoholic fatty liver disease (NAFLD) is an emerging global health problem that accompanied the obesity epidemic and is considered as the hepatic component of metabolic syndrome (MetS). Modification of lif...

    Authors: Nehal Mohamed Bahgat Gamil, Sahar Mohamed El Agaty, Gehan Khalaf Megahed, Rania Salah Mansour and Marwa Saad Abdel-Latif
    Citation: Egyptian Liver Journal 2021 11:60
  4. Congenital hepatic fibrosis (CHF) is a rare disorder of the porto-biliary system occurring due to the defective remodeling of ductal architecture leading to progressive fibrosis of the portal tract. Though cla...

    Authors: Souradeep Dutta, Ankit Jain, Reddy Abhinaya, Bheemanathi Hanuman Srinivas and Vishnu Prasad Nelamangala Ramakrishnaiah
    Citation: Egyptian Liver Journal 2021 11:59
  5. Non-alcoholic fatty liver disease remains asymptomatic until advanced disease, when risk factor modification and available treatment become no longer effective. Studies on hepatic vasculature can be informativ...

    Authors: Manal Sabry, Tarek Youssef, Mohamed Shaker, Mohamed Magdy Salama, Nourhan Assem and Christina Alfons Anwar
    Citation: Egyptian Liver Journal 2021 11:58
  6. The heterogeneous nature of human hepatocellular carcinoma (HCC) impedes both treatment strategies and prognostic predictions. Several markers have been proposed for the diagnosis of HCC. Cytoskeleton-associat...

    Authors: Maissa El Raziky, Hanan Abdel Hafez, Aisha Elsharkawy, Tarek Ahmed Moneer, Suzan M. EL-Sheikh, Rabab M. Maher and Sahar A. Sharaf
    Citation: Egyptian Liver Journal 2021 11:57
  7. Tamiflu (Oseltamivir) and Adamine (Amantadine HCl) are antiviral drugs which are used for prevention and treatment for influenza. The present study was carried out to evaluate the effect of Tamiflu and Adamine...

    Authors: Nagla Zaky Ibrahim El-Alfy, Samia Mohamed Sakr, Mahmoud Fathy Mahmoud and Heba Ahmed Omar
    Citation: Egyptian Liver Journal 2021 11:55
  8. Hepatitis C virus (HCV) infection is a major cause of liver-related morbidity and mortality among thalassemic patients. Direct-acting antiviral agents (DAAs) are highly effective and well-tolerated by chronic ...

    Authors: Elsayed Ghoneem, Ahmed Saleh, Shahira Aly El-Etreby, Metwaly Ibrahim Mortada, Mayada A. Ghannam, Shaimaa El-Ashwah and Noha Eisa
    Citation: Egyptian Liver Journal 2021 11:54
  9. Hepatitis B virus (HBV) may reactivate when treating chronic hepatitis C (CHC) with direct-acting antivirals (DAA). We aimed to investigate the risk of HBV infection and reactivation during DAA therapy by perf...

    Authors: Haitham A. Azeem, Ashraf M. Alkabeer, Ali Sobhy Mohammed and Amira Ahmed Hussein
    Citation: Egyptian Liver Journal 2021 11:53
  10. Despite the great advancement in therapeutic modalities for esophageal varices, early variceal rebleeding still occurs at high rates leading to an exaggeration of the morbidity and mortality for cirrhotic pati...

    Authors: Maha Salah Abu Alia, Abdallah Ahmed Elsawy, Reda Abdelsamaie Elarabawy and Hegazy Mohamed Hegazy
    Citation: Egyptian Liver Journal 2021 11:52
  11. Antioxidant intakes are one of the most cherished dietary approaches for the management of oxidative stress-induced liver damages. These antioxidants exist as the bioactive compounds present in plants and othe...

    Authors: Akeem Babatunde Sikiru, Arunachalam Arangasamy, Stephen Sunday Acheneje Egena, Sejian Veerasamy, Ippala Janardhan Reddy and Bhatta Raghavendra
    Citation: Egyptian Liver Journal 2021 11:51
  12. This study was conducted to check anxiety level and mental stress in the 200 confirmed hepatitis C patients during the COVID-19 pandemic. The Chinese version of the Beck Anxiety Inventory (BAI) score index was...

    Authors: Sadia Rafique, Muhammad Saleem Khan, Rabia Unar, Muhammad Wajid, Ahmad Waheed and Ali Umar
    Citation: Egyptian Liver Journal 2021 11:50
  13. Hepatocellular carcinoma and hepatitis C are strongly associated. The current work aimed to study the expression levels of microRNA-331-3p and microRNA-23b-3p as propable biomarkers for detecting liver cancer ...

    Authors: Reham A. Aboelwafa, Walid Ismail Ellakany, Marwa A. Gamaleldin and Marwa A. Saad
    Citation: Egyptian Liver Journal 2021 11:49
  14. Patients with chronic hemolytic anemias (CHA) are at a high risk for transfusion-transmitted infections. Various studies in Egypt have shown a prevalence of hepatitis C virus (HCV) infection in 24–37% of those...

    Authors: Walaa M. Hashem, Manal Hamdy El-Sayed, Ossama A. Ahmed, Hany M. Dabbous, Mohamed Kamal Shaker, Ahmed Fouad Sherief, Mary Gamal Naguib, Shereen Abdel-Monem Ibrahim and Ahmed Mansour
    Citation: Egyptian Liver Journal 2021 11:48
  15. Intrathoracic rupture of hepatic hydatid cyst is a rare but dangerous complication. Its occurrence in children is exceptional as diagnosis and management constitute real challenges. We report two cases of intr...

    Authors: Rachida Laamiri, Sahla Sellami, Nahla Kechiche, Mabrouk Abdelaali, Mongi Mekki and Mohsen Belghith
    Citation: Egyptian Liver Journal 2021 11:47
  16. Black gall stones are consistently described in relation to haem turnover and hemolytic disorders. Black gall stones are also a frequent presentation in cirrhotic patients, principally due to hemolysis-related...

    Authors: Omkolsoum Alhaddad, Maha Elsabaawy, Olfat Hendy, Ahmed Kamal and Helmy Elshazly
    Citation: Egyptian Liver Journal 2021 11:46
  17. Hepatic ischemia reperfusion (IR) injury is considered as a main cause of liver damage and dysfunction. The l-arginine/nitric oxide pathway seems to be relevant during this process of IR. Although acute intense e...

    Authors: Amr H. ELKady, Bataa M. Elkafoury, Dalia A. Saad, Doaa M. Abd el-Wahed, Walaa Baher and Mona A. Ahmed
    Citation: Egyptian Liver Journal 2021 11:45
  18. We evaluated the validity of some non-invasive scores and ultrasound findings to predict fibrosis and steatosis in a cohort of NAFLD patients who underwent liver biopsy. Ninety-seven NAFLD patients were enroll...

    Authors: Rasha Eletreby, Zeinab Abdellatif, Yasmine Gaber, Ahmed Ramadan, Naglaa Ahmad, Hany Khattab, Mohamed Said and Yasmin Saad
    Citation: Egyptian Liver Journal 2021 11:44
  19. In Egypt, an endemic country for both viral hepatitis C and B infections, infection could be more prevalent in pregnant females. This study aimed to assess the prevalence of chronic HCV and HBV in a cohort of ...

    Authors: Rasha Eletreby, Maged Abd Elraouf, Ahmed Fouad, Mona Nasser, Mostafa Al Bassiouni, Naglaa Zayed, Ayman Yosry and Zeinab Abdellatif
    Citation: Egyptian Liver Journal 2021 11:43
  20. Chronic hepatitis C virus (HCV) infection has been linked to cardiovascular disease (CVD). However, CVD risk prediction in chronic HCV-infected patients is problematic as the prevalence of different cardiac bi...

    Authors: Amira Isaac, Basant Elmarashly, Kadry El Saeed, Rasha Samir Mohamed, Shereen Abdelmonem Ibrahim and Eslam Safwat
    Citation: Egyptian Liver Journal 2021 11:42
  21. Hepatocellular carcinoma is the most common primary liver malignancy, with the highest incidence in the developing world, including Egypt. Hepatocellular carcinoma is usually diagnosed in the terminal stage of...

    Authors: Ashraf Khalil, Ashraf Elfert, Samar Ghanem, Marwa Helal, Shymaa Abdelsattar, Gamalate Elgedawy, Manar Obada, Mohamed Abdel-Samiee and Hala El-Said
    Citation: Egyptian Liver Journal 2021 11:41

    The Correction to this article has been published in Egyptian Liver Journal 2021 11:68

  22. Liver transplantation (LT) is the best treatment for selected patients with cirrhosis and small hepatocellular carcinoma (HCC) who are not candidates for resection. The proinflammatory effects of systemic infl...

    Authors: Nourhan Badwei, Waheed A. Monsef, Iman Montasser, Mohamed Bahaa, Mahmoud El Meteini and Shimaa Y. Kamel
    Citation: Egyptian Liver Journal 2021 11:40
  23. Hepatitis E virus (HEV) is an important cause of acute liver failure (ALF) in Bangladesh with pregnant mothers being more vulnerable. As HEV occurs in epidemics, it limits medical capabilities in this resource...

    Authors: Debashis Chowdhury, Farhana Mahmood, Cathryn Edwards and Simon D. Taylor-Robinson
    Citation: Egyptian Liver Journal 2021 11:39
  24. Several genetic polymorphisms have been proven to play a key role in the progression of non-alcoholic fatty liver disease (NAFLD) from simple steatosis to NASH with fibrosis. Our aim was to study the effect of...

    Authors: Eman M. Hasan, Rasha A. Abd Al Aziz, Dina Sabry, Hedy A. Badary, Yasmine Gaber, Ayman Yosry and Zeinab Zakaria
    Citation: Egyptian Liver Journal 2021 11:37
  25. Celiac trunk agenesis is the recent and the rarest vascular variation reported. Reported cases in literature were identified either incidentally on imaging or while cadaveric dissections. This is a unique expe...

    Authors: Fizzah Arif, Shah Muhammad, Muhammad Arsalan Khan and Abdaal Waseem Khan
    Citation: Egyptian Liver Journal 2021 11:36
  26. Hepatitis C virus infection is a global health challenge with Egypt being one of the highly affected countries. IL-10 has been suggested as a suitable marker to assess necroinflammation and to monitor the prog...

    Authors: Iman S. Naga, Amel Abdel Fattah Kamel, Said Ahmed Ooda, Hadeer Muhammad Fath Elbab and Rania Mohamed El-Sharkawy
    Citation: Egyptian Liver Journal 2021 11:35
  27. Hepatorenal syndrome is a potentially fatal complication of advanced liver disease. Markers for early diagnosis and identification of high-risk patients are lacking. Our aim was to evaluate the role of renal D...

    Authors: Mohamad Sherif Mogawer, Sahar Abdel Rahman Nassef, Samah Mohamad Abd Elhamid, Shaimaa Elkholy, Nahla Emad Abd El Aziz, Ula Mabid Al-Jarhi and Abeer Awad Abdellatif
    Citation: Egyptian Liver Journal 2021 11:34
  28. Bacterial translocation is considered the pathophysiological hallmark in the development of spontaneous bacterial peritonitis (SBP). Prokinetics can increase gastrointestinal (GIT) motility, reduce small bowel...

    Authors: Afaf Y. M. Younes, Sherief Abd-Elsalam, Gehan F. Attia and Mona A. H. Shehata
    Citation: Egyptian Liver Journal 2021 11:33
  29. Hepatitis C virus (HCV) infection is considered one of the main causes of chronic liver diseases. HCV is responsible for 25% of HCC cases worldwide. DAAs represent an important step for HCV eradication. The ai...

    Authors: Nancy Abdel Fattah Ahmed, Ahmed Shawky Hassan Ali, Rizk Ahmed El Baz and Islam Abd El-Hamid El-Zayyadi
    Citation: Egyptian Liver Journal 2021 11:31
  30. Post-variceal band ligation bleeding ulcer is a severe complication with considerable mortality. We tried evaluating self-expandable metallic stent (SEMS) with concern to the ulcer morphology not well studied.

    Authors: Osama Elbahr, Ahmad Kamal, Ayman Alsebaey, Mohamed Amin, Mohamed Abbasy, Ahmad Edris, Ali Nada, Alyaa Sabry, Sameh Afiffy, Abd El-Aleem Helal, Mohamad Abd El-aziz and Abd El-naser Gad-Allah
    Citation: Egyptian Liver Journal 2021 11:30
  31. Spontaneous bacterial peritonitis (SBP) is an ascitic fluid infection in patients with liver cirrhosis in the absence of surgical causes. The drop of the ascitic fluid polymorphonuclear leukocyte count (AFPC) ...

    Authors: Hanaa Mostafa Badran, Maha Mohammad Elsabaawy, Mohamed Azazy Mahmoud, Heba Samy Ghanem, Ayman Alsebaey and Warda Othman
    Citation: Egyptian Liver Journal 2021 11:29
  32. Radiofrequency is one of the curative treatment options for hepatocellular carcinoma (HCC). Despite the progressive improvements in the efficacy of radiofrequency, the survival of patients with HCC who undergo...

    Authors: N. A. Abdelkader, M. H. Abdelaleem, M. A. Abo El-maaty, S. A. Sayed and H. I. Aly
    Citation: Egyptian Liver Journal 2021 11:28
  33. Gastroesophageal reflux disease (GERD) is one of the most common diseases in modern civilization that originates basically from a disturbance in the structure and function of the lower esophageal sphincter (LE...

    Authors: Taha M. Hassanin, Yasser Foaud, Hala Mohamed, Zienab Saad, Amr Elsayed, Sara Refaei and Wael Soliman
    Citation: Egyptian Liver Journal 2021 11:27
  34. Cure of chronic hepatitis C (HCV) in HIV/HCV co-infected patients is a priority due to their increased risk of complications. Daclatasvir and sofosbuvir treatment regimens with or without ribavirin are conside...

    Authors: Inas E L-Khedr Mohamed, Kadry Mohamed EL-Saeed, Mahmoud Hassan Al-Sadik and Christina Alphonse Anwar
    Citation: Egyptian Liver Journal 2021 11:26
  35. The prevention of portal hypertensive complications, including upper gastrointestinal bleeding, is critically important and achieved only through the use of upper endoscopy for the management of oesophageal ga...

    Authors: Yasir M Khayyat
    Citation: Egyptian Liver Journal 2021 11:25
  36. Acute liver failure (ALF) is a syndromic diagnosis, consisting of jaundice, coagulopathy, and any degree of encephalopathy in a patient without pre-existing liver disease within 26 weeks of the onset of sympto...

    Authors: Akash Roy, Sunil Taneja, Arka De, Ashim Das, Ajay K. Duseja and Virendra Singh
    Citation: Egyptian Liver Journal 2021 11:24
  37. Accurate assessment of GFR is critical in patients with chronic liver disease for early detection of renal disease. Cystatin C is a marker of GFR that seems to be more accurate than creatinine. The aim of the ...

    Authors: Mona Abd El-Rahman Abu El-Makarem, Mahmoud Mohamed Mousa, Lion Azer Ayaad and Hesham K. H. Keryakos
    Citation: Egyptian Liver Journal 2021 11:23
  38. Tumor-associated macrophages (TAMs), inflammatory cells in tumor microenvironment, are crucial for the tumor occurrence and progression which in turn increase the expression of soluble CD163 (sCD163). Neverthe...

    Authors: Marwa Ahmed Sakr, Khaled Abdel Hamid Mohamed, Ahmed Mohamed Hussein, Mohamed Hassan Fouad, Ahmed Samir Allam and Eslam Safwat
    Citation: Egyptian Liver Journal 2021 11:22
  39. Chronic liver diseases are common worldwide, especially in developing countries. The rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)/(COVID-19) leads to the infection of many patie...

    Authors: Samy Zaky, Mohamed Alboraie, Mohamed El Badry, Mohamed A. Metwally, Ahmed Abdelaziz, Yasser Fouad, Sherief Abd-Elsalam, Abdelmajeed Mahmoud, Gamal Shiha, Amin Abdel Baki, Mohamed El Kassas and Gamal Esmat
    Citation: Egyptian Liver Journal 2021 11:21
  40. Successful eradication of hepatitis C virus (HCV) has great impact on the prognosis of HCV-related complications and the associated mortality. The development of the new direct-acting antiviral drugs (DAAs) ha...

    Authors: Asmaa M. Elbrolosy, Moamena S. Elhamouly, Emad M. Eed, Gamalat A. El Gedawy, Mai Abozeid and Naglaa S. Elabd
    Citation: Egyptian Liver Journal 2021 11:19
  41. Hepatic encephalopathy exacerbates the morbidity, delays hospital discharge, and increases the rate of readmissions of cirrhotic patients, particularly those are admitted by acute variceal bleeding. We evaluat...

    Authors: Rehab Elsayed Elsafty, Abdallah Ahmed Elsawy, Ahmed Fawzy Selim and Atef Mohamed Taha
    Citation: Egyptian Liver Journal 2021 11:18
  42. Hepatitis C virus, a silent killer, has infected 71 million people globally. The recombinant viral antigenic proteins might be used in the early diagnosis of HCV infection. The NS3 and NS5A genes of HCV functi...

    Authors: Sabeen Sabri, Muhammad Idrees Khan, Shazia Rafique, Amjad Ali and Muhammad Saleem Khan
    Citation: Egyptian Liver Journal 2021 11:17
  43. Non-alcoholic fatty liver disease (NAFLD) is the most epidemic liver disorder worldwide as a result of rapid lifestyle transformation over the past few decades and is expected to elevate in the next few years ...

    Authors: Fayed Attia Koutb Megahed, Xiaoling Zhou, Pingnan Sun and Marwa Mohamed Elmaghrabi
    Citation: Egyptian Liver Journal 2021 11:16
  44. Interleukin-4 (IL-4), a pleiotropic anti-inflammatory cytokine, is produced mainly by activated T helper 2 (Th2). Hepatocellular carcinoma (HCC) is a typical inflammation-related cancer. Alterations influencin...

    Authors: Mohy-Eldin Abd-Elfattah, Mary Naguib, Mohammed Elkheer, Eman Abdelsameea and Ali Nada
    Citation: Egyptian Liver Journal 2021 11:15
  45. Viral resistance-associated substitutions (RASs) can develop in the setting of DAAs therapy (i.e., emerging RASs). Long-term monitoring of fibrosis regression after achieving SVR to simiprevir (SMV)/sofosbuvir...

    Authors: Nahed A. Makhlouf, Mohamed Farouk, Hanan Mohamed Nafeh, Ahmad Farooq Alsayed Hasanain, Mohamed Ahmed El-Mokhtar, Helal F. Hetta, Mohamed A. Mekky, Mohamed Alboraie, Hussein ELamin and Ahmed Medhat Nasr
    Citation: Egyptian Liver Journal 2021 11:13

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