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Egyptian Liver Journal
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Articles

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  1. Therapeutic interventions for hepatocellular carcinoma (HCC) particularly in patients with advanced liver disease may lead to more aggravation of clinical and biochemical parameters of liver functions. We aime...

    Authors: Amr Shaaban Hanafy, Mohamed Sorour Mohamed, Mohamed Abu Taleb, H. M. Mohammed, Tarek M. H. Ibrahim, Sameh Saber and Hesham A. Atia
    Citation: Egyptian Liver Journal 2021 11:83
    Content type: Original Research Article Published on:

  2. Hepatitis C virus (HCV) infection is a high prevalent disease. Sofosbuvir/ledipasvir (SOF/LDV) can successfully treat HCV and it was until recently that SOF/LDV was approved by the FDA in haemodialysis patient...

    Authors: Ebtisam Boushi, Khaled Cheha, Noha Hedar, Rasha Almokdad, Mohammed Waleed Alassi and Ameer Kakaje
    Citation: Egyptian Liver Journal 2021 11:82
    Content type: Original Research Article Published on:

  3. The most common primary liver cancer in adults is hepatocellular carcinoma (HCC) which is commonly presented with a poor prognosis. Therefore, it is important to explore effective biomarkers and therapeutic ta...

    Authors: Ayman El Shayeb, Akram Deghedy, Essam Saeed Bedewy, Sahar Badawy and Nermeen Abdeen
    Citation: Egyptian Liver Journal 2021 11:81
    Content type: Original Research Article Published on:

  4. Abnormal extracellular matrix (ECM) turnover is linked to liver fibrosis as it reflects an imbalance between repair and progressive substitution of the liver parenchyma by scar tissue. Matrix metalloproteinase...

    Authors: Ola Galal Behairy, Mohamed Mostafa El-Bakry, Amira Ibrahim Mansour, Amira M. N. Abdelrahman and Ghada Mansour Emam
    Citation: Egyptian Liver Journal 2021 11:80
    Content type: Original Research Article Published on:

  5. Chronic hepatitis C is the most common cause of chronic liver disease and hepatocellular carcinoma in Egypt. A pathogenic link with gut microbial dysbiosis has been described in different diseases. The aim of ...

    Authors: Khaled Mohieldeen, Soraya Abdel Fatah Hamoda, Shwikar Mahmoud Ahmed, Abdurrahman Najeeb and Walid Ismail Ellakany
    Citation: Egyptian Liver Journal 2021 11:79
    Content type: Original Research Article Published on:

  6. Non-alcoholic fatty liver disease (NAFLD) is one of the most prevalent chronic liver diseases, particularly in Egypt. It is defined as the accumulation of lipids inside the hepatocytes, in the absence of other...

    Authors: Manal Sabry Mohamed, Tarek Mohammed Youssef, Esraa Ebrahim Abdullah and Ahmed Elmetwally Ahmed
    Citation: Egyptian Liver Journal 2021 11:78
    Content type: Original Research Article Published on:

  7. The World Health Organization (WHO) aims to achieve global hepatitis C elimination by 2030, defined as diagnosis of 90% of infected individuals and treating 80% of them. Current guidelines for the screening an...

    Authors: Ouafa Kallala, Saoussen Kacem, Imene Fodha, Bruno Pozzetto and Trabelsi Abdelhalim
    Citation: Egyptian Liver Journal 2021 11:77
    Content type: Original Research Article Published on:

  8. The combination of endoscopic band ligation and beta-blockers is the standard of care treatment for secondary prevention of variceal bleeding; however, rebleeding still occurs with associated high mortality. S...

    Authors: Helmy Elshazly, Hasan Zaghlah, El-Sayed Tharwa, Ahmed Abuamer, Dina Nor-Eldin, Reem El Sheemy and Mohamed El Kassas
    Citation: Egyptian Liver Journal 2021 11:76
    Content type: Original Research Article Published on:

  9. Killer cell immunoglobulin-like receptors (KIR) are considered to be the key receptors that control the development and function of human natural killer cells which play complex mechanisms in autoimmune diseas...

    Authors: Ola Galal Behairy, Ola Samir El-Shimi, Naglaa Hamed Shalan and Shaymaa Mohamed Baghdady
    Citation: Egyptian Liver Journal 2021 11:75
    Content type: Original Research Article Published on:

  10. The long-term health consequences of coronavirus disease 2019 (COVID-19) are still unclear. The majority of previous trials addressed the post-COVID-19 symptoms through comprehensive medical questionnaires for...

    Authors: Mohammed Ali Gameil, Rehab Elsayed Marzouk, Ahmed Hassan Elsebaie and Salah Eldeen Rozaik
    Citation: Egyptian Liver Journal 2021 11:74
    Content type: Original Research Article Published on:

  11. Dieulafoy arteriole is a lamina propria vessel that unlike the other arterioles is getting bigger and bending into the mucosa of the gastrointestinal tract. Such anatomic aberration is unusual cause for life t...

    Authors: Omkolsoum Alhaddad, Maha Elsabaawy, Ahmed Elfaioumy and Ashraf Eljaky
    Citation: Egyptian Liver Journal 2021 11:73
    Content type: Case report Published on:

  12. Bile acids are essential organic molecules synthesized from cholesterol in the liver and regarded as indicators of hepatobiliary impairment; however, their role in the pathogenesis of hepatocellular carcinoma ...

    Authors: Ashraf Khalil, Azza Elsheashaey, Eman Abdelsameea, Manar Obada, F. F. Mohamed Bayomy and Hala El-Said
    Citation: Egyptian Liver Journal 2021 11:72
    Content type: Original Research Article Published on:

  13. A large number of chronic hepatitis C patients had been successfully treated by directly acting antivirals; therefore, strategies for the long-term follow-up of these patients have to be planned based on the p...

    Authors: Nadia Abdel Ataay Abdelkader, Osama Ashraf Ahmed, Ahmed Fouad Sherief, Doaa Mahmoud Kandil, Mohammed Soliman Gado and Amira Mahmoud Al Balakosy
    Citation: Egyptian Liver Journal 2021 11:71
    Content type: Original Research Article Published on:

  14. Liver transplantation (LT) is the only effective radical cure for all types of end-stage liver diseases. Major advances have been made in the field of liver transplantation due to improvements in surgical tech...

    Authors: Azza Abd El-rahman Saab, Eman Saleh El-hadidi, Maha Mohsen Hussein, Maram Saeed Abd El-baki Shararah and Heba Hassan Aly
    Citation: Egyptian Liver Journal 2021 11:70
    Content type: Original Research Article Published on:

  15. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection mainly affects respiratory system. Later, liver affection has also been reported in the form of marked elevated liver enzymes. However, th...

    Authors: Dina Sweed, Mohamed Ramadan El Shanshory, Eman Mohammed Elaskary, Hassnaa Atef Hassan, Enas Sweed, Eman Sweed, Shimaa Abdelsattar, Ahmed Abdelgawad, Asmaa Mosbeh, Heba Abdallah, Shereen El-Mashad and Nermine Ehsan
    Citation: Egyptian Liver Journal 2021 11:69
    Content type: Case report Published on:

  17. Nogo-B is one of the members of the reticulon family. Nogo-B influences the proliferation of the hepatic stellate cells inducing liver fibrotic changes. We aimed at measuring the serum levels of Nogo-B in pati...

    Authors: Ayman Fouad, Wael Aref, Ahmed Elshenawy, Hadeel M. Hanafi, Khaled M. Attallah and Alshaimaa Rezk L. R. Alnaggar
    Citation: Egyptian Liver Journal 2021 11:67
    Content type: Original Research Article Published on:

  18. Wilson’s disease is a multisystem disorder with predominant clinical symptoms depending on the site of copper deposition in the body. Hepatic presentation is usually seen in the younger age group. And pancreat...

    Authors: Sanjay Kumar, Sridhar Sundaram, Harish Darak, Suprabhat Giri and Shobna Bhatia
    Citation: Egyptian Liver Journal 2021 11:66
    Content type: Case report Published on:

  19. Chronic hepatitis C (CHC) virus is associated with insulin resistance and diabetes which have been linked to progressive liver fibrosis and sustained virologic response (SVR) to antiviral treatment. Resistin i...

    Authors: Amira Isaac, Khaled Hamdy Abd El-Mageed, Hany Haroun Kaisar, Hany Samir Rasmy, Ramy Samir Abd Elhamid Ghait, Ibrahim Magdy Ibrahim and George Safwat Riad
    Citation: Egyptian Liver Journal 2021 11:65
    Content type: Original Research Article Published on:

  20. The pandemic of COVID19 which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first described in China as an unexplained pneumonia transmitted by respiratory droplets. Gastrointes...

    Authors: Dina Sweed, Eman Abdelsameea, Esraa A. Khalifa, Heba Abdallah, Heba Moaz, Inas Moaz, Shimaa Abdelsattar, Nadine Abdel-Rahman, Asmaa Mosbeh, Hussein A. Elmahdy and Eman Sweed
    Citation: Egyptian Liver Journal 2021 11:64
    Content type: Review Published on:

  21. Several conditions are associated with esophageal eosinophilia such as eosinophilic esophagitis (EoE) and gastro-esophageal reflux disease (GERD). The aim of this study was to detect the prevalence of esophage...

    Authors: Nancy Abdel Fattah Ahmed, Hebat-Allah Moheb Amer, Dina Abdallah Ibrahim and Islam Abd El-Hamid El-Zayyadi
    Citation: Egyptian Liver Journal 2021 11:63
    Content type: Original Research Article Published on:

  22. Chronic hepatitis C virus (HCV) infection represents a major health-related burden in Egypt. HCV is considered as a major cardiovascular risk factor. BNP (B-type natriuretic peptide) has been determined as a c...

    Authors: Ali Nada, Aliaa Sabry, Naglaa S. Elabd, Azza M. Abdu Allah, Nada Elnaidany and Mohamed Abbasy
    Citation: Egyptian Liver Journal 2021 11:62
    Content type: Original Research Article Published on:

  23. Around 25% of the world population was affected by the metabolic-related fatty liver disorder. Hepatic steatosis is frequently observed in conjunction with hypertension, obesity comorbidities, and diabetes. We...

    Authors: Asmaa Ali, Mona Hasan, Shaimaa Hamed and Amir Elhamy
    Citation: Egyptian Liver Journal 2021 11:61
    Content type: Original Research Article Published on:

  24. Non-alcoholic fatty liver disease (NAFLD) is an emerging global health problem that accompanied the obesity epidemic and is considered as the hepatic component of metabolic syndrome (MetS). Modification of lif...

    Authors: Nehal Mohamed Bahgat Gamil, Sahar Mohamed El Agaty, Gehan Khalaf Megahed, Rania Salah Mansour and Marwa Saad Abdel-Latif
    Citation: Egyptian Liver Journal 2021 11:60
    Content type: Original Research Article Published on:

  25. Congenital hepatic fibrosis (CHF) is a rare disorder of the porto-biliary system occurring due to the defective remodeling of ductal architecture leading to progressive fibrosis of the portal tract. Though cla...

    Authors: Souradeep Dutta, Ankit Jain, Reddy Abhinaya, Bheemanathi Hanuman Srinivas and Vishnu Prasad Nelamangala Ramakrishnaiah
    Citation: Egyptian Liver Journal 2021 11:59
    Content type: Case report Published on:

  26. Non-alcoholic fatty liver disease remains asymptomatic until advanced disease, when risk factor modification and available treatment become no longer effective. Studies on hepatic vasculature can be informativ...

    Authors: Manal Sabry, Tarek Youssef, Mohamed Shaker, Mohamed Magdy Salama, Nourhan Assem and Christina Alfons Anwar
    Citation: Egyptian Liver Journal 2021 11:58
    Content type: Original Research Article Published on:

  27. The heterogeneous nature of human hepatocellular carcinoma (HCC) impedes both treatment strategies and prognostic predictions. Several markers have been proposed for the diagnosis of HCC. Cytoskeleton-associat...

    Authors: Maissa El Raziky, Hanan Abdel Hafez, Aisha Elsharkawy, Tarek Ahmed Moneer, Suzan M. EL-Sheikh, Rabab M. Maher and Sahar A. Sharaf
    Citation: Egyptian Liver Journal 2021 11:57
    Content type: Original Research Article Published on:

  29. Tamiflu (Oseltamivir) and Adamine (Amantadine HCl) are antiviral drugs which are used for prevention and treatment for influenza. The present study was carried out to evaluate the effect of Tamiflu and Adamine...

    Authors: Nagla Zaky Ibrahim El-Alfy, Samia Mohamed Sakr, Mahmoud Fathy Mahmoud and Heba Ahmed Omar
    Citation: Egyptian Liver Journal 2021 11:55
    Content type: Original Research Article Published on:

  30. Hepatitis C virus (HCV) infection is a major cause of liver-related morbidity and mortality among thalassemic patients. Direct-acting antiviral agents (DAAs) are highly effective and well-tolerated by chronic ...

    Authors: Elsayed Ghoneem, Ahmed Saleh, Shahira Aly El-Etreby, Metwaly Ibrahim Mortada, Mayada A. Ghannam, Shaimaa El-Ashwah and Noha Eisa
    Citation: Egyptian Liver Journal 2021 11:54
    Content type: Original Research Article Published on:

  31. Hepatitis B virus (HBV) may reactivate when treating chronic hepatitis C (CHC) with direct-acting antivirals (DAA). We aimed to investigate the risk of HBV infection and reactivation during DAA therapy by perf...

    Authors: Haitham A. Azeem, Ashraf M. Alkabeer, Ali Sobhy Mohammed and Amira Ahmed Hussein
    Citation: Egyptian Liver Journal 2021 11:53
    Content type: Original Research Article Published on:

  32. Despite the great advancement in therapeutic modalities for esophageal varices, early variceal rebleeding still occurs at high rates leading to an exaggeration of the morbidity and mortality for cirrhotic pati...

    Authors: Maha Salah Abu Alia, Abdallah Ahmed Elsawy, Reda Abdelsamaie Elarabawy and Hegazy Mohamed Hegazy
    Citation: Egyptian Liver Journal 2021 11:52
    Content type: Original Research Article Published on:

  33. Antioxidant intakes are one of the most cherished dietary approaches for the management of oxidative stress-induced liver damages. These antioxidants exist as the bioactive compounds present in plants and othe...

    Authors: Akeem Babatunde Sikiru, Arunachalam Arangasamy, Stephen Sunday Acheneje Egena, Sejian Veerasamy, Ippala Janardhan Reddy and Bhatta Raghavendra
    Citation: Egyptian Liver Journal 2021 11:51
    Content type: Original Research Article Published on:

  34. This study was conducted to check anxiety level and mental stress in the 200 confirmed hepatitis C patients during the COVID-19 pandemic. The Chinese version of the Beck Anxiety Inventory (BAI) score index was...

    Authors: Sadia Rafique, Muhammad Saleem Khan, Rabia Unar, Muhammad Wajid, Ahmad Waheed and Ali Umar
    Citation: Egyptian Liver Journal 2021 11:50
    Content type: Original Research Article Published on:

  35. Hepatocellular carcinoma and hepatitis C are strongly associated. The current work aimed to study the expression levels of microRNA-331-3p and microRNA-23b-3p as propable biomarkers for detecting liver cancer ...

    Authors: Reham A. Aboelwafa, Walid Ismail Ellakany, Marwa A. Gamaleldin and Marwa A. Saad
    Citation: Egyptian Liver Journal 2021 11:49
    Content type: Original Research Article Published on:

  36. Patients with chronic hemolytic anemias (CHA) are at a high risk for transfusion-transmitted infections. Various studies in Egypt have shown a prevalence of hepatitis C virus (HCV) infection in 24–37% of those...

    Authors: Walaa M. Hashem, Manal Hamdy El-Sayed, Ossama A. Ahmed, Hany M. Dabbous, Mohamed Kamal Shaker, Ahmed Fouad Sherief, Mary Gamal Naguib, Shereen Abdel-Monem Ibrahim and Ahmed Mansour
    Citation: Egyptian Liver Journal 2021 11:48
    Content type: Original Research Article Published on:

  37. Intrathoracic rupture of hepatic hydatid cyst is a rare but dangerous complication. Its occurrence in children is exceptional as diagnosis and management constitute real challenges. We report two cases of intr...

    Authors: Rachida Laamiri, Sahla Sellami, Nahla Kechiche, Mabrouk Abdelaali, Mongi Mekki and Mohsen Belghith
    Citation: Egyptian Liver Journal 2021 11:47
    Content type: Case report Published on:

  38. Black gall stones are consistently described in relation to haem turnover and hemolytic disorders. Black gall stones are also a frequent presentation in cirrhotic patients, principally due to hemolysis-related...

    Authors: Omkolsoum Alhaddad, Maha Elsabaawy, Olfat Hendy, Ahmed Kamal and Helmy Elshazly
    Citation: Egyptian Liver Journal 2021 11:46
    Content type: Case report Published on:

  39. Hepatic ischemia reperfusion (IR) injury is considered as a main cause of liver damage and dysfunction. The l-arginine/nitric oxide pathway seems to be relevant during this process of IR. Although acute intense e...

    Authors: Amr H. ELKady, Bataa M. Elkafoury, Dalia A. Saad, Doaa M. Abd el-Wahed, Walaa Baher and Mona A. Ahmed
    Citation: Egyptian Liver Journal 2021 11:45
    Content type: Original Research Article Published on:

  40. We evaluated the validity of some non-invasive scores and ultrasound findings to predict fibrosis and steatosis in a cohort of NAFLD patients who underwent liver biopsy. Ninety-seven NAFLD patients were enroll...

    Authors: Rasha Eletreby, Zeinab Abdellatif, Yasmine Gaber, Ahmed Ramadan, Naglaa Ahmad, Hany Khattab, Mohamed Said and Yasmin Saad
    Citation: Egyptian Liver Journal 2021 11:44
    Content type: Original Research Article Published on:

  41. In Egypt, an endemic country for both viral hepatitis C and B infections, infection could be more prevalent in pregnant females. This study aimed to assess the prevalence of chronic HCV and HBV in a cohort of ...

    Authors: Rasha Eletreby, Maged Abd Elraouf, Ahmed Fouad, Mona Nasser, Mostafa Al Bassiouni, Naglaa Zayed, Ayman Yosry and Zeinab Abdellatif
    Citation: Egyptian Liver Journal 2021 11:43
    Content type: Original Research Article Published on:

  42. Chronic hepatitis C virus (HCV) infection has been linked to cardiovascular disease (CVD). However, CVD risk prediction in chronic HCV-infected patients is problematic as the prevalence of different cardiac bi...

    Authors: Amira Isaac, Basant Elmarashly, Kadry El Saeed, Rasha Samir Mohamed, Shereen Abdelmonem Ibrahim and Eslam Safwat
    Citation: Egyptian Liver Journal 2021 11:42
    Content type: Original Research Article Published on:

  43. Hepatocellular carcinoma is the most common primary liver malignancy, with the highest incidence in the developing world, including Egypt. Hepatocellular carcinoma is usually diagnosed in the terminal stage of...

    Authors: Ashraf Khalil, Ashraf Elfert, Samar Ghanem, Marwa Helal, Shymaa Abdelsattar, Gamalate Elgedawy, Manar Obada, Mohamed Abdel-Samiee and Hala El-Said
    Citation: Egyptian Liver Journal 2021 11:41
    Content type: Review Published on:

    The Correction to this article has been published in Egyptian Liver Journal 2021 11:68

  44. Liver transplantation (LT) is the best treatment for selected patients with cirrhosis and small hepatocellular carcinoma (HCC) who are not candidates for resection. The proinflammatory effects of systemic infl...

    Authors: Nourhan Badwei, Waheed A. Monsef, Iman Montasser, Mohamed Bahaa, Mahmoud El Meteini and Shimaa Y. Kamel
    Citation: Egyptian Liver Journal 2021 11:40
    Content type: Original Research Article Published on:

  45. Hepatitis E virus (HEV) is an important cause of acute liver failure (ALF) in Bangladesh with pregnant mothers being more vulnerable. As HEV occurs in epidemics, it limits medical capabilities in this resource...

    Authors: Debashis Chowdhury, Farhana Mahmood, Cathryn Edwards and Simon D. Taylor-Robinson
    Citation: Egyptian Liver Journal 2021 11:39
    Content type: Original Research Article Published on:

  47. Several genetic polymorphisms have been proven to play a key role in the progression of non-alcoholic fatty liver disease (NAFLD) from simple steatosis to NASH with fibrosis. Our aim was to study the effect of...

    Authors: Eman M. Hasan, Rasha A. Abd Al Aziz, Dina Sabry, Hedy A. Badary, Yasmine Gaber, Ayman Yosry and Zeinab Zakaria
    Citation: Egyptian Liver Journal 2021 11:37
    Content type: Original Research Article Published on:

  48. Celiac trunk agenesis is the recent and the rarest vascular variation reported. Reported cases in literature were identified either incidentally on imaging or while cadaveric dissections. This is a unique expe...

    Authors: Fizzah Arif, Shah Muhammad, Muhammad Arsalan Khan and Abdaal Waseem Khan
    Citation: Egyptian Liver Journal 2021 11:36
    Content type: Case report Published on:

  49. Hepatitis C virus infection is a global health challenge with Egypt being one of the highly affected countries. IL-10 has been suggested as a suitable marker to assess necroinflammation and to monitor the prog...

    Authors: Iman S. Naga, Amel Abdel Fattah Kamel, Said Ahmed Ooda, Hadeer Muhammad Fath Elbab and Rania Mohamed El-Sharkawy
    Citation: Egyptian Liver Journal 2021 11:35
    Content type: Original Research Article Published on:

  50. Hepatorenal syndrome is a potentially fatal complication of advanced liver disease. Markers for early diagnosis and identification of high-risk patients are lacking. Our aim was to evaluate the role of renal D...

    Authors: Mohamad Sherif Mogawer, Sahar Abdel Rahman Nassef, Samah Mohamad Abd Elhamid, Shaimaa Elkholy, Nahla Emad Abd El Aziz, Ula Mabid Al-Jarhi and Abeer Awad Abdellatif
    Citation: Egyptian Liver Journal 2021 11:34
    Content type: Original Research Article Published on:
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  • ISSN: 2090-6226 (electronic)