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  1. HCV infection is a major worldwide cause of chronic liver diseases. Esophageal and gastric varices are common in cirrhotic patients due to concomitant portal hypertension. Variceal hemorrhage is a major decomp...

    Authors: Ashraf Aboismail, Mohamed El-Shazly, Nasser Abdallah, Eman Elsayed and Rania Abo-Yossef
    Citation: Egyptian Liver Journal 2022 12:7
  2. Lately, the humanity has been being threatened by the coronavirus disease (COVID-19). The virus-related destructive motives can damage not only the lungs but also the brain, blood vessels, kidneys, and the heart.

    Authors: Omkolsoum Alhaddad, Maha Elsabaawy, Ahmed Edrees, Essam Elshimy, Dalia Elsabaawy and Tarek Mansour
    Citation: Egyptian Liver Journal 2022 12:5
  3. Acute cellular rejection beyond the 6th month posttransplant is an uncommon complication after liver transplantation. The inadequate immunosuppression (IS) remains the main risk factor. We report a case of acu...

    Authors: Chantelli Iamblaudiot Razafindrazoto, Noémie Trystram, Gustavo Miranda Martins, Christiane Stern, Frédéric Charlotte and Pascal Lebray
    Citation: Egyptian Liver Journal 2022 12:4
  4. Unexplained biliary dilatation (UBD) frequently represents a diagnostic dilemma. Linear endosonography (EUS), with its close proximity to the pancreaticobiliary system and the ability for tissue acquisition, c...

    Authors: Hassan Atalla, Ayman Menessy, Hazem Hakim, Hideyuki Shiomi, Yuzo Kodama and Elsayed Ghoneem
    Citation: Egyptian Liver Journal 2022 12:3
  5. Isolation of post-partum umbilical cord Wharton’s jelly stem cells has gained attention as an alternative source of the bone marrow. Because easy isolation, lack of ethical concerns, and the presence of both e...

    Authors: Hager Abouelnaga, Doaa El-Khateeb, Yasmine Moemen, Ashraf El-Fert, Mohamed Elgazzar and Ashraf Khalil
    Citation: Egyptian Liver Journal 2022 12:2
  6. Neonatal cholestasis (NC) is a major cause of morbidity and mortality in young infants. This study examines the etiology of NC and its outcome during 2 years of follow-up at a tertiary referral center in Bangl...

    Authors: Salahuddin Mahmud, Jahida Gulshan, Mashud Parvez, Farhana Tasneem and Syed Shafi Ahmed
    Citation: Egyptian Liver Journal 2022 12:1

    The Correction to this article has been published in Egyptian Liver Journal 2022 12:15

  7. Liver biopsy is the standard reference for staging hepatic fibrosis. Non-invasive methods for assessment of hepatic fibrosis and cirrhosis are becoming increasingly popular.

    Authors: Mohamed Alboraie, Marwa Khairy, Aisha Elsharkawy, Noha Asem, Mohamed El Kassas, Abdelaleem A. Elgendy, Hanaa Nagdy, Zakarya Shady, Ahmed Eliwa, Amira R. El-Ansary, Mohamed Ibrahem, Mahmoud A. Allam, Abdelhalim Elsherif, Fathy Elghamry, Fuad Hassan, Mohamed Hassany…
    Citation: Egyptian Liver Journal 2021 11:94
  8. Stem cells are widely used for therapy including treatment of liver damage. Adipose-derived mesenchymal stem cells (ADMSCs) administered to treat fatty liver are known to improve liver function but their use i...

    Authors: Aliasgar Hatimbhai Vohra, Kapil Kumar Upadhyay, Apeksha Suhas Joshi, Hitarthi Swetang Vyas, Jaymesh Thadani and Ranjitsinh Vijaysinh Devkar
    Citation: Egyptian Liver Journal 2021 11:93
  9. Solid organ transplantation (SOT) service has been disrupted during the current coronavirus disease 2019 (COVID-19) pandemic, which deferred the service in most centers worldwide. As the pandemic persists, the...

    Authors: Abeer Awad Abdellatif, Mohamad Sherif Mogawer, Mostafa El- Shazli, Hanaa El-Karaksy, Ayman Salah, Amany Abdel-Maqsod, Mona El-Amir, Mohamed Said, Naglaa Zayed, Karim Hosny, Hadeel Gamal Eldeen, Ayman M. A. Osman, Doaa A. Mansour, Ahmed Nabil, Ahmed Abdel-Ghani, Engy A. Mogahed…
    Citation: Egyptian Liver Journal 2021 11:92
  10. Chronic hepatitis B (CHB) is associated with many serious clinical and social consequences. Despite Egypt being classified as a country of low endemicity, the infection is associated with a 15–25% risk of prem...

    Authors: Jackleen Azer Abd El-Halim, Gihan Ismael Gewaifel, Eman Ahmed Fawzy Darwish, Ahmed Maher Ramadan and Gihan Hamdy ElSisi
    Citation: Egyptian Liver Journal 2021 11:91
  11. PVT is an ultrasonographic finding in up to 8% of patients with liver cirrhosis. Once hepatocellular carcinoma has occurred as the final station in liver cirrhosis, the risk of PVT rises to 40%. Benign and mal...

    Authors: Amr Shaaban Hanafy and Essam Elsayed Tharwat
    Citation: Egyptian Liver Journal 2021 11:90
  12. Ruptured esophageal varices (EVs) are a leading cause of death in Portal hypertension (PHT), it has been a big concern of research to screen EVs through non-invasive approaches. This study aimed to evaluate th...

    Authors: Lerine B. El Shazli, Dina A. Ragab, Karim A. Abdelhady and Asmaa W. Abdelaziz
    Citation: Egyptian Liver Journal 2021 11:89
  13. Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. There are multiple factors that could affect the malignancy and progression of HCC including tumor number, size, and macrovascular inva...

    Authors: Mohamed Eltabbakh, Heba M. Abdella, Safaa Askar, Mohamed A. Abuhashima and Mohamed K. Shaker
    Citation: Egyptian Liver Journal 2021 11:87
  14. Accurate staging in individuals infected with hepatitis C is imperative to understand their long-term risk for liver-related complications. Liver biopsy has a traditional role to determine the levels of liver ...

    Authors: Tamer A. Addissouky, Yuliang Wang, Fayed Attia Koutb Megahed, Ayman E. El Agroudy, Ibrahim El Tantawy El Sayed and Abdel Moneim A. K. El-Torgoman
    Citation: Egyptian Liver Journal 2021 11:86
  15. Nonalcoholic fatty liver disease (NAFLD) is proved to be related to insulin resistance and type 2 diabetes, and it is also not rare in individuals without diabetes. The present study attempts to identify the m...

    Authors: H. Naguib and H. Kassab
    Citation: Egyptian Liver Journal 2021 11:85
  16. Liver cirrhosis is divided into two stages: compensated stage and another advanced stage which includes both decompensated cirrhosis and acute-on-chronic liver failure. The immune system is of major importance...

    Authors: Ayman El-Shayeb, Sawsan El-Mallah, Akram Deghady, Samar El-Hewely and Doaa Elwazzan
    Citation: Egyptian Liver Journal 2021 11:84
  17. Therapeutic interventions for hepatocellular carcinoma (HCC) particularly in patients with advanced liver disease may lead to more aggravation of clinical and biochemical parameters of liver functions. We aime...

    Authors: Amr Shaaban Hanafy, Mohamed Sorour Mohamed, Mohamed Abu Taleb, H. M. Mohammed, Tarek M. H. Ibrahim, Sameh Saber and Hesham A. Atia
    Citation: Egyptian Liver Journal 2021 11:83
  18. Hepatitis C virus (HCV) infection is a high prevalent disease. Sofosbuvir/ledipasvir (SOF/LDV) can successfully treat HCV and it was until recently that SOF/LDV was approved by the FDA in haemodialysis patient...

    Authors: Ebtisam Boushi, Khaled Cheha, Noha Hedar, Rasha Almokdad, Mohammed Waleed Alassi and Ameer Kakaje
    Citation: Egyptian Liver Journal 2021 11:82
  19. The most common primary liver cancer in adults is hepatocellular carcinoma (HCC) which is commonly presented with a poor prognosis. Therefore, it is important to explore effective biomarkers and therapeutic ta...

    Authors: Ayman El Shayeb, Akram Deghedy, Essam Saeed Bedewy, Sahar Badawy and Nermeen Abdeen
    Citation: Egyptian Liver Journal 2021 11:81
  20. Abnormal extracellular matrix (ECM) turnover is linked to liver fibrosis as it reflects an imbalance between repair and progressive substitution of the liver parenchyma by scar tissue. Matrix metalloproteinase...

    Authors: Ola Galal Behairy, Mohamed Mostafa El-Bakry, Amira Ibrahim Mansour, Amira M. N. Abdelrahman and Ghada Mansour Emam
    Citation: Egyptian Liver Journal 2021 11:80
  21. Chronic hepatitis C is the most common cause of chronic liver disease and hepatocellular carcinoma in Egypt. A pathogenic link with gut microbial dysbiosis has been described in different diseases. The aim of ...

    Authors: Khaled Mohieldeen, Soraya Abdel Fatah Hamoda, Shwikar Mahmoud Ahmed, Abdurrahman Najeeb and Walid Ismail Ellakany
    Citation: Egyptian Liver Journal 2021 11:79
  22. Non-alcoholic fatty liver disease (NAFLD) is one of the most prevalent chronic liver diseases, particularly in Egypt. It is defined as the accumulation of lipids inside the hepatocytes, in the absence of other...

    Authors: Manal Sabry Mohamed, Tarek Mohammed Youssef, Esraa Ebrahim Abdullah and Ahmed Elmetwally Ahmed
    Citation: Egyptian Liver Journal 2021 11:78
  23. The World Health Organization (WHO) aims to achieve global hepatitis C elimination by 2030, defined as diagnosis of 90% of infected individuals and treating 80% of them. Current guidelines for the screening an...

    Authors: Ouafa Kallala, Saoussen Kacem, Imene Fodha, Bruno Pozzetto and Trabelsi Abdelhalim
    Citation: Egyptian Liver Journal 2021 11:77
  24. The combination of endoscopic band ligation and beta-blockers is the standard of care treatment for secondary prevention of variceal bleeding; however, rebleeding still occurs with associated high mortality. S...

    Authors: Helmy Elshazly, Hasan Zaghlah, El-Sayed Tharwa, Ahmed Abuamer, Dina Nor-Eldin, Reem El Sheemy and Mohamed El Kassas
    Citation: Egyptian Liver Journal 2021 11:76
  25. Killer cell immunoglobulin-like receptors (KIR) are considered to be the key receptors that control the development and function of human natural killer cells which play complex mechanisms in autoimmune diseas...

    Authors: Ola Galal Behairy, Ola Samir El-Shimi, Naglaa Hamed Shalan and Shaymaa Mohamed Baghdady
    Citation: Egyptian Liver Journal 2021 11:75
  26. The long-term health consequences of coronavirus disease 2019 (COVID-19) are still unclear. The majority of previous trials addressed the post-COVID-19 symptoms through comprehensive medical questionnaires for...

    Authors: Mohammed Ali Gameil, Rehab Elsayed Marzouk, Ahmed Hassan Elsebaie and Salah Eldeen Rozaik
    Citation: Egyptian Liver Journal 2021 11:74
  27. Dieulafoy arteriole is a lamina propria vessel that unlike the other arterioles is getting bigger and bending into the mucosa of the gastrointestinal tract. Such anatomic aberration is unusual cause for life t...

    Authors: Omkolsoum Alhaddad, Maha Elsabaawy, Ahmed Elfaioumy and Ashraf Eljaky
    Citation: Egyptian Liver Journal 2021 11:73
  28. Bile acids are essential organic molecules synthesized from cholesterol in the liver and regarded as indicators of hepatobiliary impairment; however, their role in the pathogenesis of hepatocellular carcinoma ...

    Authors: Ashraf Khalil, Azza Elsheashaey, Eman Abdelsameea, Manar Obada, F. F. Mohamed Bayomy and Hala El-Said
    Citation: Egyptian Liver Journal 2021 11:72
  29. A large number of chronic hepatitis C patients had been successfully treated by directly acting antivirals; therefore, strategies for the long-term follow-up of these patients have to be planned based on the p...

    Authors: Nadia Abdel Ataay Abdelkader, Osama Ashraf Ahmed, Ahmed Fouad Sherief, Doaa Mahmoud Kandil, Mohammed Soliman Gado and Amira Mahmoud Al Balakosy
    Citation: Egyptian Liver Journal 2021 11:71
  30. Liver transplantation (LT) is the only effective radical cure for all types of end-stage liver diseases. Major advances have been made in the field of liver transplantation due to improvements in surgical tech...

    Authors: Azza Abd El-rahman Saab, Eman Saleh El-hadidi, Maha Mohsen Hussein, Maram Saeed Abd El-baki Shararah and Heba Hassan Aly
    Citation: Egyptian Liver Journal 2021 11:70
  31. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection mainly affects respiratory system. Later, liver affection has also been reported in the form of marked elevated liver enzymes. However, th...

    Authors: Dina Sweed, Mohamed Ramadan El Shanshory, Eman Mohammed Elaskary, Hassnaa Atef Hassan, Enas Sweed, Eman Sweed, Shimaa Abdelsattar, Ahmed Abdelgawad, Asmaa Mosbeh, Heba Abdallah, Shereen El-Mashad and Nermine Ehsan
    Citation: Egyptian Liver Journal 2021 11:69
  32. Nogo-B is one of the members of the reticulon family. Nogo-B influences the proliferation of the hepatic stellate cells inducing liver fibrotic changes. We aimed at measuring the serum levels of Nogo-B in pati...

    Authors: Ayman Fouad, Wael Aref, Ahmed Elshenawy, Hadeel M. Hanafi, Khaled M. Attallah and Alshaimaa Rezk L. R. Alnaggar
    Citation: Egyptian Liver Journal 2021 11:67
  33. Wilson’s disease is a multisystem disorder with predominant clinical symptoms depending on the site of copper deposition in the body. Hepatic presentation is usually seen in the younger age group. And pancreat...

    Authors: Sanjay Kumar, Sridhar Sundaram, Harish Darak, Suprabhat Giri and Shobna Bhatia
    Citation: Egyptian Liver Journal 2021 11:66
  34. Chronic hepatitis C (CHC) virus is associated with insulin resistance and diabetes which have been linked to progressive liver fibrosis and sustained virologic response (SVR) to antiviral treatment. Resistin i...

    Authors: Amira Isaac, Khaled Hamdy Abd El-Mageed, Hany Haroun Kaisar, Hany Samir Rasmy, Ramy Samir Abd Elhamid Ghait, Ibrahim Magdy Ibrahim and George Safwat Riad
    Citation: Egyptian Liver Journal 2021 11:65
  35. The pandemic of COVID19 which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first described in China as an unexplained pneumonia transmitted by respiratory droplets. Gastrointes...

    Authors: Dina Sweed, Eman Abdelsameea, Esraa A. Khalifa, Heba Abdallah, Heba Moaz, Inas Moaz, Shimaa Abdelsattar, Nadine Abdel-Rahman, Asmaa Mosbeh, Hussein A. Elmahdy and Eman Sweed
    Citation: Egyptian Liver Journal 2021 11:64
  36. Several conditions are associated with esophageal eosinophilia such as eosinophilic esophagitis (EoE) and gastro-esophageal reflux disease (GERD). The aim of this study was to detect the prevalence of esophage...

    Authors: Nancy Abdel Fattah Ahmed, Hebat-Allah Moheb Amer, Dina Abdallah Ibrahim and Islam Abd El-Hamid El-Zayyadi
    Citation: Egyptian Liver Journal 2021 11:63
  37. Chronic hepatitis C virus (HCV) infection represents a major health-related burden in Egypt. HCV is considered as a major cardiovascular risk factor. BNP (B-type natriuretic peptide) has been determined as a c...

    Authors: Ali Nada, Aliaa Sabry, Naglaa S. Elabd, Azza M. Abdu Allah, Nada Elnaidany and Mohamed Abbasy
    Citation: Egyptian Liver Journal 2021 11:62
  38. Around 25% of the world population was affected by the metabolic-related fatty liver disorder. Hepatic steatosis is frequently observed in conjunction with hypertension, obesity comorbidities, and diabetes. We...

    Authors: Asmaa Ali, Mona Hasan, Shaimaa Hamed and Amir Elhamy
    Citation: Egyptian Liver Journal 2021 11:61
  39. Non-alcoholic fatty liver disease (NAFLD) is an emerging global health problem that accompanied the obesity epidemic and is considered as the hepatic component of metabolic syndrome (MetS). Modification of lif...

    Authors: Nehal Mohamed Bahgat Gamil, Sahar Mohamed El Agaty, Gehan Khalaf Megahed, Rania Salah Mansour and Marwa Saad Abdel-Latif
    Citation: Egyptian Liver Journal 2021 11:60
  40. Congenital hepatic fibrosis (CHF) is a rare disorder of the porto-biliary system occurring due to the defective remodeling of ductal architecture leading to progressive fibrosis of the portal tract. Though cla...

    Authors: Souradeep Dutta, Ankit Jain, Reddy Abhinaya, Bheemanathi Hanuman Srinivas and Vishnu Prasad Nelamangala Ramakrishnaiah
    Citation: Egyptian Liver Journal 2021 11:59
  41. Non-alcoholic fatty liver disease remains asymptomatic until advanced disease, when risk factor modification and available treatment become no longer effective. Studies on hepatic vasculature can be informativ...

    Authors: Manal Sabry, Tarek Youssef, Mohamed Shaker, Mohamed Magdy Salama, Nourhan Assem and Christina Alfons Anwar
    Citation: Egyptian Liver Journal 2021 11:58
  42. The heterogeneous nature of human hepatocellular carcinoma (HCC) impedes both treatment strategies and prognostic predictions. Several markers have been proposed for the diagnosis of HCC. Cytoskeleton-associat...

    Authors: Maissa El Raziky, Hanan Abdel Hafez, Aisha Elsharkawy, Tarek Ahmed Moneer, Suzan M. EL-Sheikh, Rabab M. Maher and Sahar A. Sharaf
    Citation: Egyptian Liver Journal 2021 11:57
  43. Tamiflu (Oseltamivir) and Adamine (Amantadine HCl) are antiviral drugs which are used for prevention and treatment for influenza. The present study was carried out to evaluate the effect of Tamiflu and Adamine...

    Authors: Nagla Zaky Ibrahim El-Alfy, Samia Mohamed Sakr, Mahmoud Fathy Mahmoud and Heba Ahmed Omar
    Citation: Egyptian Liver Journal 2021 11:55
  44. Hepatitis C virus (HCV) infection is a major cause of liver-related morbidity and mortality among thalassemic patients. Direct-acting antiviral agents (DAAs) are highly effective and well-tolerated by chronic ...

    Authors: Elsayed Ghoneem, Ahmed Saleh, Shahira Aly El-Etreby, Metwaly Ibrahim Mortada, Mayada A. Ghannam, Shaimaa El-Ashwah and Noha Eisa
    Citation: Egyptian Liver Journal 2021 11:54
  45. Hepatitis B virus (HBV) may reactivate when treating chronic hepatitis C (CHC) with direct-acting antivirals (DAA). We aimed to investigate the risk of HBV infection and reactivation during DAA therapy by perf...

    Authors: Haitham A. Azeem, Ashraf M. Alkabeer, Ali Sobhy Mohammed and Amira Ahmed Hussein
    Citation: Egyptian Liver Journal 2021 11:53
  46. Despite the great advancement in therapeutic modalities for esophageal varices, early variceal rebleeding still occurs at high rates leading to an exaggeration of the morbidity and mortality for cirrhotic pati...

    Authors: Maha Salah Abu Alia, Abdallah Ahmed Elsawy, Reda Abdelsamaie Elarabawy and Hegazy Mohamed Hegazy
    Citation: Egyptian Liver Journal 2021 11:52
  47. This study was conducted to check anxiety level and mental stress in the 200 confirmed hepatitis C patients during the COVID-19 pandemic. The Chinese version of the Beck Anxiety Inventory (BAI) score index was...

    Authors: Sadia Rafique, Muhammad Saleem Khan, Rabia Unar, Muhammad Wajid, Ahmad Waheed and Ali Umar
    Citation: Egyptian Liver Journal 2021 11:50

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