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Table 4 Comparison of laboratory investigations results between patients with and without CMV or EBV coinfection (n = 110)

From: Epstein–Barr virus and cytomegalovirus coinfection in Egyptian COVID-19 patients

 

Either CMV or EBV

P

Negative

Positive

Mean ± SD

(min–max)

Median (IQR)

Mean ± SD

(min–max)

Median (IQR)

TLC

9.3376 ± 9.3454 (2.6–89.8)

8 (4.9–11.1)

6.38 ± 3.0195 (0.7–10.6)

6.3 (4.8–9.3)

.257

Lymphocytes

1.4588 ± 1.0757 (0.34–6.8)

1.1 (0.8–1.6)

1.1333 ± 0.9802 (0.04–3.17)

0.94 (0.8–1)

.271

Neutrophils

7.2056 ± 8.8012 (0–82.8)

5.505 (3.7–8.8)

4.4422 ± 2.5959 (0.58–7.7)

4.6 (2.1–5.91)

.200

RBCs

4.8831 ± 0.6437 (3.23–6.44)

4.84 (4.4–5.24)

4.8771 ± 1.0164 (2.97–6.29)

4.83 (4.67–5.59)

.781

Hb

12.8786 ± 1.803 (7.9–18.5)

13 (12–14.2)

12.26 ± 2.9923 (6.9–15.5)

13.45 (10–13.9)

.992

Platelets

205 ± 88 (41–439)

186 (141–257)

139 ± 49 (51–199)

141 (117–185)

.021*

CRP

79.0638 ± 60.4708 (2.3–384)

96 (32–96)

125.81 ± 74.96(42.2–241)

96 (70.55–195.1)

.096

S. ferritin

438 ± 359 (10–1200)

340 (109–752)

1407 ± 1617 (245–4805)

621 (395–1776)

.053

D-dimer

1124 ± 1333 (187–7237)

636 (440–1126)

1076 ± 586 (450–1970)

916 (598–1579)

.223

1st_h_ESR

23 ± 5 (15–26)

25 (20–26)

90 ± 17 (80–110)

80 (80–110)

.057

2nd_h_ESR

35 ±  (35–35)

35 (35–35)

106 ± (106–106)

106 (106–106)

1.000

Total bilirubin

1.0327 ± 0.6929 (0.4–3.8)

0.8 (0.6–1.15)

1 ± 0.6693 (0.5–2.3)

0.85 (0.5–1)

.919

Direct bilirubin

0.5922 ± 0.5879 (0.1–2.8)

0.3 (0.3–0.7)

0.3833 ± 0.2787 (0.1–0.8)

0.35 (0.1–0.6)

.538

ALT

74 ± 59 (14–326)

58 (36–81)

83 ± 94 (14–338)

50 (42–94)

.860

AST

79 ± 42 (29–315)

66 (53–96)

118 ± 201 (13–684)

53 (40–92)

.128

Serum albumin

3.815 ± 0.5713 (2.2–4.9)

3.8 (3.5–4.2)

3.1333 ± 1.0113 (1.8–4.8)

3.05 (2.6–3.5)

.039*

ALP

87 ± 36 (33–182)

76 (72–97)

106 ± 32 (62–150)

103 (86–134)

.177

GGT

118 ± 139 (23–532)

60 (41–148)

105 ± 109 (28–182)

105 (28–182)

.933

PT

15.1785 ± 1.8999 (12.3–21.4)

15.4 (13.3–16.1)

16 ± 1.186 (14.5–17)

16.25 (15.05–16.95)

.258

INR

1.251 ± 0.2372 (0.85–1.95)

1.27 (1.06–1.36)

1.252 ± 0.1297 (1–1.42)

1.27 (1.2–1.37)

.810

  1. Mann-Whitney U test was used
  2. TLC total leucocytic count, RBCs red blood cells, Hb hemoglobin, CRP C-reactive protein, ESR erythrocyte sedimentation rate. ALT alanine aminotransferase, AST aspartate aminotransferase, ALP alkaline phosphatase, GGT gamma glutamyl transferase, PT prothrombin time, INR International Normalized Ratio