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Table 3 Baseline characteristics of patients with HE without AKI versus those with AKI

From: The urine albumin creatinine ratio is one of the predictors of acute kidney injury in hepatitis C-related cirrhotic hepatic encephalopathy

Variables

HE with no AKI

n=51

HE-AKI

n=16

P value

Age, years

Median (IQR)

59 (16)

60.5 (9)

0.139

Sex, n (%)

 Males

24 (47.1%)

12 (75%)

 

 Females

27 (52.9%)

4 (25%)

0.051

AS T, median (IQR)

48 (38)

64.5 (132)

0.112

ALT, median (IQR)

32 (28)

34 (32.4)

0.546

Serum albumin, median (IQR)

2.3 (0.9)

2.25 (0.58)

0.680

Total bilirubin, median (IQR)

1.8 (3.3)

4.6 (3.9)

0.005

INR, median (IQR)

1.66 (0.7)

2 (0.7)

0.078

CTP score, median (IQR)

9 (3)

11 (1.75)

< 0.001

CTP class, n (%)

 B

 C

28 (54.9%)

23 (45.1%)

0 (0%)

16 (100%)

< 0.001

MELD score, mean (SD)

16 (5.4)

20.9 (4.1)

0.313

Baseline serum creatinine, median (IQR)

0.9 (0.4)

1.15 (0.38)

0.004

UACR, median (IQR)

39 (46.6)

249 (256.6)

< 0.001

Hospital length of stay, n (%)

 ≤ 7 days

 8–14 days

47 (92.2%)

4 (7.8%)

9 (56.3%)

7 (43.8%)

0.001

Mortality, n (%)

9 (17.6%)

13 (81.3%)

< 0.001

  1. HE hepatic encephalopathy, n number, AKI acute kidney injury, IQR interquartile range, AST aspartate aminotransferase, ALT alanine aminotransferase, INR international normalized ratio, CTP Child-Turcotte-Pugh, MELD model of end-stage liver disease, UACR urine albumin creatinine ratio