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Table 2 Correlation between the studied biomarkers and the characteristics of the HCC group

From: Study on molecular expression of long non-coding RNA Glypican3 in hepatocellular cancer patients

 

GPC3

lncRNA AF085935

Low expression (n = 34)

High expression

(n = 36)

p value

Low expression (n = 34)

High expression

(n = 36)

p value

Age

57 ± 7

57.8 ± 6.5

0.6

58.8 ± 7.6

56 ± 5.7

0.1

Gender

Male

30 (88.2%)

30 (83.3%)

0.55

29 (85.3%)

31 (86.1%)

0.9

Female

4 (11.8%)

6 (16.7%)

5 (14.7%)

5 (13.9%)

Child Score

A

25 (73.5%)

0 (0%)

 < 0.001

25 (73.5%)

0 (0%)

 < 0.001

B

9 (26.5%)

3 (8%)

6 (17.6%)

3 (8.4%)

C

0 (0%)

33 (92%)

3 (8.9%)

33 (91.6%)

No. of FLs

1

19 (55.9%)

22 (61.1)

0.015

21 (61.8%)

20 (55.6)

0.12

2

10 (29.4%)

2 (5.6%)

8 (23.5%)

4 (11.1%)

multiple

5 (14.7%)

12 (33.3%)

5 (14.7%)

12 (33.3%)

AFP

 < 20

20 (58.8%)

15 (41.7%)

0.15

15 (44.1%)

20 (55.6%)

0.33

 > 20

14 (41.2%)

21 (58.3%)

19 (55.9%)

16 (44.4%)

Vascular invasion

Yes

3 (8.8%)

5 (13.9%)

0.5

6 (17.6%)

34 (94.4%)

0.003

No

31 (92.2%)

31 (86.1%)

28 (82.4%)

2 (5.6%)

Abdominal LNs

Yes

2 (5.9%)

6 (16.7%)

 < 0.001

7 (20.6%)

35 (97.2%)

0.019

No

32(94.1%)

30(83.3%)

27(79.4%)

1(2.8%)

  1. The median expression level was used as the cutoff. Low expression of lncRNA and GPC3 in 70 patients was defined as a value below the 50th percentile, and high expression was defined as a value above the 50th percentile