The impact of polymorphism in PNPLA3 and TM6SF2 genes on the susceptibility and survival of hepatitis C-related hepatocellular carcinoma

Egyptian Liver Journal

Table 5 Univariate and multivariate regression analysis of the risk factors of HCC

	^aOR	95% C.I		P value	^bOR	95% C.I		P value
	^aOR	Lower bound	Upper bound	P value	^bOR	Lower bound	Upper bound	P value
Gender (male)	2.918	1.723	4.941	0.001**	0.525	0.218	1.266	0.1
Smoker	3.671	1.861	7.242	0.001**	0.363	0.112	1.179	0.09
BMI	0.959	0.909	1.011	0.1	0.710	0.253	1.996	0.5
DM	1.721	.960	3.086	0.05*	1.016	1.006	1.026	0.001**
AFP	1.021	1.013	1.029	0.001**	0.247	0.019	3.176	0.1

Body mass index (BMI), diabetes mellitus (DM), and alpha-fetoprotein (AFP). OR odds ratio, C.I confidence interval, P value was calculated depending on logistic regression analysis. *P value <0.05 is significant, **P value <0.01 is highly significant. ^aOR for univariate analysis, ^bOR for multivariate analysis