Table 4 Association of BCLC staging with genotype distribution of the studied genes

PNPLA3

CC

26 (46.4%)

21 (47.7%)

8 (50.0%)

2 (50.0%)

57 (47.5%)

0.8

CG

21 (37.5%)

19 (43.2%)

7 (43.8%)

1 (25.0%) ^aa

48 (40.0%)

GG

9 (16.1%) ^{aa, bb}

4 (9.1%) ^{aa, bb}

1 (6.3%) ^{aa, bb}

1 (25.0%) ^aa

15 (12.5%)

C Allele

73 (0.652)

61 (0.693)

23 (0.719)

5 (0.625)

162 (0.675)

0.7

G Allele

39 (0.348) ^**

27 (0.307) ^**

9 (0.281) ^**

3 (0.375) ^**

78 (0.325)

TM6SF2

CC

41 (73.2%)

32 (72.7%)

7 (43.8%)

4 (100.0%)

84 (70.0%)

0.2

CT

11 (19.6%) ^aa

9 (20.5%) ^aa

8 (50.0%)

0 (0.0%) ^aa

28 (23.3%)

TT

4 (7.1%) ^{aa, bb}

3 (6.8%) ^{aa, bb}

1 (6.3%) ^{aa, bb}

0 (0.0%) ^aa

8 (6.7%)

C Allele

93 (0.830)

73 (0.830)

22 (0.688)

8 (1.000)

196 (0.817)

0.03*

T Allele

19 (0.170) ^**

15 (0.170) ^**

10 (0.313) ^**

0 (0.000)

44 (0.183)