Skip to main content

Table 3 Comparison between the different studied groups according to predictive non-invasive liver cirrhosis scores

From: Diagnostic validity of serum YKL-40 as a non-invasive diagnostic marker of oesophageal varices in cirrhotic hepatitis C virus patients

 

Group I (n = 20)

Group II (n = 20)

Group IIIa (n = 20)

Group IV (n = 20)

Test of sig.

p

FIB-4

 Min.–max.

3.16–4.15

3.17–4.48

3.34–11.53

0.22–0.83

H = 62.963*

< 0.001*

 Mean ± SD.

3.37 ± 0.22

3.52 ± 0.39

5.58 ± 2.04

0.42 ± 0.15

 Median (IQR)

3.29 (3.25–3.47)

3.37 (3.30–3.51)

4.90 (4.14–6.92)

0.42 (0.31–0.48)

p0

< 0.001*

< 0.001*

< 0.001*

   

Sig.bet.Grps

p1 = 0.317, p2 < 0.001*, p3 < 0.001*

   

APRI

 Min.–max.

0.74–2.34

1.03–1.77

1.14–6.75

0.06–0.30

H = 53.436*

< 0.001*

 Mean ± SD.

1.32 ± 0.45

1.30 ± 0.25

2.25 ± 1.32

0.15 ± 0.06

 Median (IQR)

1.23 (1.03–1.64)

1.19 (1.10–1.52)

1.81 (1.37–2.83)

0.14 (0.11–0.16)

p0

< 0.001*

< 0.001*

< 0.001*

   

Sig.bet.Grps

p1 = 0.814, p2 = 0.007*, p3 = 0.014*

   

PLT/spleen diameter

 Min.–max.

931.20–1357.10

812.50–1364.20

268.40–1050.0

1758.30–3536.3

F = 126.160*

< 0.001*

 Mean ± SD.

1158.92 ± 139.22

1023.83 ± 160.86

645.83 ± 253.64

2404.40±508.86

 Median (IQR)

1119.95 (1056.6–1271.4)

946.85 (906.2–1149.95)

607.88 (442.60–853.10)

2349.95 (1987.5–2813.3)

p0

< 0.001*

< 0.001*

< 0.001*

   

Sig.bet.Grps

p1 = 0.499, p2 < 0.001*, p3 = 0.001*

   

AST/ALT ratio

 Min.–max.

1.26–4.50

1.27–3.84

0.77–3.25

0.37–0.95

F = 37.712*

< 0.001*

 Mean ± SD.

2.40 ± 0.87

2.20 ± 0.61

1.46 ± 0.63

0.65 ± 0.14

 Median (IQR)

2.19 (1.78–2.99)

2.26 (1.91–2.41)

1.21 (1.12–1.57)

0.63 (0.57–0.74)

p0

< 0.001*

< 0.001*

0.001*

   

Sig.bet.Grps

p1 = 0.499, p2 < 0.001*, p3 < 0.001*

   
  1. H: H for Kruskal-Wallis test, pairwise comparison between each 2 groups was done using post hoc test (Dunn’s for multiple comparisons test)
  2. F: F for ANOVA test, pairwise comparison between each 2 groups was done using post hoc test (Tukey)
  3. p: p value for comparing between the studied groups
  4. p0: p value for comparing between groups IV and each other group
  5. p1: p value for comparing between groups I and II
  6. p2: p value for comparing between groups I and III
  7. p3: p value for comparing between groups II and III
  8. *Statistically significant at p ≤ 0.05
  9. IQR interquartile range, SD standard deviation
  10. Group I: cirrhosis without varices
  11. Group II: cirrhosis with small varices (I, II)
  12. Group IIIa: cirrhosis with large varices (III, IV)
  13. Group IV: control