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Table 1 Change of parameters throughout the study checkpoints

From: Effect of achieving sustained virological response with direct-acting antiviral agents on glycemic control in diabetic patients with chronic hepatitis C infection

Laboratory results Baseline EOT 12 weeks after EOT Comparing 3 timelines Comparing Baseline to EOT Comparing
Baseline to 12 weeks after EOT
Comparing
EOT to 12 weeks after EOT
Test
value
P value Sig Test
value
P value Sig Test
value
P value Sig Test
value
P value Sig
No. = 46 No. = 46 No. = 46
F Ins Median (IQR) 14.75 (9.50–22.60) 10.35 (8.60–16.00) 13.75 (9.00–18.20) 13.978b 0.001 HS − 3.534d 0.000 HS − 2.009d 0.044 S − 2.005d 0.045 S
Range 2.8–35 3.1–31.4 1.9–33
FBS Mean ± SD 154.08 ± 42.95 150.23 ± 74.40 157.95 ± 55.62 0.584a 0.528 NS 0.487c 0.629 NS − 0.739c 0.463 NS − 0.972c 0.336 NS
Range 90–286 78–392 95–360
HOMA Median (IQR) 5.25 (3.35–7.65) 3.74 (2.59–5.45) 4.83 (3.72–6.66) 17.522b 0.000 HS − 3.436d 0.001 HS − 1.579d 0.114 NS − 2.212d 0.027 S
Range 0.92–24.72 0.64–30.39 0.47–25.42
2hpp Mean ± SD 244.28 ± 55.16 235.04 ± 85.30 246.33 ± 69.81 0.802a 0.448 NS 0.894c 0.376 NS − 0.230c 0.819 NS − 1.229c 0.225 NS
Range 156–398 124–535 145–397.8
HbA1c Mean ± SD 7.56 ± 1.01 7.00 ± 1.52 7.57 ± 1.17 5.980a 0.006 HS 2.592c 0.013 S − 0.052c 0.958 NS − 3.911c 0.000 HS
Range 5.1–9.63 4.5–11 5.6–11.3
T Chol Mean ± SD 156.98 ± 43.41 172.37 ± 36.64 173.89 ± 42.62 7.169a 0.002 HS − 3.235c 0.002 HS − 3.128c 0.003 HS − 0.329c 0.744 NS
Range 77–276 95–253 89–266
TGs Mean ± SD 105.63 ± 33.80 110.15 ± 33.31 112.65 ± 38.49 1.554a 0.217 NS − 1.092c 0.281 NS − 1.706c 0.095 NS − 0.650c 0.519 NS
Range 50–218 66–215 31–230
HDL Mean ± SD 44.15 ± 11.13 44.97 ± 7.30 43.22 ± 9.94 0.647a 0.520 NS − 0.488c 0.628 NS 0.613c 0.543 NS 1.241c 0.221 NS
Range 23–73 27–61 20–70.4
LDL Mean ± SD 91.97 ± 36.09 105.73 ± 30.64 110.19 ± 33.50 8.908a 0.000 HS − 2.831c 0.007 HS − 4.064c 0.000 HS − 1.079c 0.286 NS
Range 36–201.2 47–178.8 44–194.6
  1. P value > 0.05 non-significant, P value < 0.05: significant, P value < 0.01 highly significant
  2. aRepeated measure ANOVA test,
  3. bFriedman test
  4. cPaired t test
  5. dWilcoxon rank test