Table 7 ROC curve predicting reversibility of portal hypertension in patients with HCV-related cirrhosis with CSPH
Variables | AUC | 95% CI | Sig. | Cutoff value | Sensitivity | Specificity | PPV | NPV |
|---|---|---|---|---|---|---|---|---|
Laboratory values | ||||||||
Platelet count | 0.853 | 0.705 to 0.945 | < 0.001 | > 73 | 83.33% | 81.25% | 87 | 76.5 |
Noninvasive markers | ||||||||
Child-Pugh score | 0.848 | 0.699 to 0.941 | < 0.001 | ≤ 7 | 62.5% | 93.75% | 93.7 | 62.5 |
PC/SD ratio | 0.891 | 0.751 to 0.967 | < 0.001 | > 524 | 70.83% | 100% | 100 | 69.6 |
Lok index | 0.714 | 0.549 to 0.845 | 0.012 | ≤ 3.15 | 83.33% | 56.25% | 74.1 | 69.2 |
Portal vein duplex and spleen diameter | ||||||||
PVD | 0.863 | 0.718 to 0.951 | < 0.001 | ≤ 14 | 50.00% | 100% | 100 | 57.1 |
PVV | 0.9 | 0.763 to 0.972 | < 0.001 | > 11 | 91.67% | 75% | 84.6 | 85.7 |
Spleen diameter | 0.868 | 0.724 to 0.954 | < 0.001 | ≤ 15.5 | 66.67% | 93.75% | 94.1 | 65.2 |