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Table 3 Comparison between improved and deceased groups regarding quantitative variables

From: Utility of prognostic scores in predicting short-term mortality in patients with acute-on-chronic liver failure

  Improved (n=64) Deceased (n=185) P
Age (years) 50.7 ± 12.1 55.0 ± 12.9 0.022
Total bilirubin (mg/dl) 20.8 ± 6.7 21.5 ± 7.0 0.482
Albumin (g/dl) 2.7 ± 0.6 2.3 ± 0.5 <0.0001
ALT (IU/l) 113.5 (19–1521) 148 (15–3850) 0.040
AST (IU/l) 83.5 (12–1937) 78 (6–3000) 0.877
ALP (IU/l) 164 (55–663) 149 (6–2080) 0.379
GGT (IU/l) 61 (15–1315) 57 (6-1549) 0.157
Hemoglobin (g/dl) 11.1 ± 1.8 10.7 ± 2.0 0.195
WBCs (×103/mm3) 11.3 ± 6.8 15.2 ± 7.7 <0.0001
Neutrophils (×103/mm3) 7.3 ± 4.1 12.5 ± 4.4 < 0.001
Platelets (×103/mm3) 163.9 ± 108.8 134.5 ± 89.3 0.034
INR 1.7 ± 0.6 2.2 ± 0.9 <0.0001
Creatinine (mg/dl) 1.4 ± 1.9 3.2 ± 2.0 <0.0001
ESR (mm/h) 14.3 ± 5.7 20.2± 5.7 < 0.001
CRP (mg/l) 15.2 ± 6.81 46.6 ± 5.4 < 0.001
NLR 2.2 ± 0.7 5.5 ± 1.6 < 0.001
Na (mEq/l) 132.4 ± 6.1 123.7 ± 8.6 <0.0001
MAP (mmHg) 79.7 ± 9.8 70.4 ± 15.7 <0.0001
Total ICU stay (days) 10.8 ± 6.4 6.8 ± 4.8 <0.0001
Total hospital stay (days) 11.9 ± 7.5 12 ± 7.8 0.937
Child-Pugh score 10.4 ± 1.2 12.3 ± 1.2 <0.0001
MELD 13.3 ± 2.6 18.7 ± 3.6 <0.0001
CLIF-C OF score 8.6 ± 1.2 11.3 ± 1.7 <0.0001
CLIF-C ACLF score 42.8 ± 8.2 55.6 ± 8.0 <0.0001
CLIF-C AD score 56.0 ± 12.1 76.1 ± 11.0 <0.0001
CLIF-SOFA score 7.1 ± 1.1 9.3 ± 1.8 <0.0001
  1. ACLF Acute-on-chronic liver failure, AD Acute decompensation, ALP Alkaline phosphatase, ALT Alanine aminotransferase, AST Aspartate aminotransferase, BP Blood pressure, CLIF-C Chronic liver failure consortium, GGT Gamma-glutamyl transferase, ICU Intensive care unit, ESR Erythrocyte sedimentation rate, CRP C-reactive protein, NLR Neutrophil-lymphocyte ratio, MAP Mean arterial pressure, MELD Model for end-stage liver disease, Na Sodium, OF Organ failure, PaO2 Partial pressure of arterial oxygen, SOFA Sequential organ failure assessment, WBCs White blood cells