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Table 3 Comparison between improved and deceased groups regarding quantitative variables

From: Utility of prognostic scores in predicting short-term mortality in patients with acute-on-chronic liver failure

 

Improved (n=64)

Deceased (n=185)

P

Age (years)

50.7 ± 12.1

55.0 ± 12.9

0.022

Total bilirubin (mg/dl)

20.8 ± 6.7

21.5 ± 7.0

0.482

Albumin (g/dl)

2.7 ± 0.6

2.3 ± 0.5

<0.0001

ALT (IU/l)

113.5 (19–1521)

148 (15–3850)

0.040

AST (IU/l)

83.5 (12–1937)

78 (6–3000)

0.877

ALP (IU/l)

164 (55–663)

149 (6–2080)

0.379

GGT (IU/l)

61 (15–1315)

57 (6-1549)

0.157

Hemoglobin (g/dl)

11.1 ± 1.8

10.7 ± 2.0

0.195

WBCs (×103/mm3)

11.3 ± 6.8

15.2 ± 7.7

<0.0001

Neutrophils (×103/mm3)

7.3 ± 4.1

12.5 ± 4.4

< 0.001

Platelets (×103/mm3)

163.9 ± 108.8

134.5 ± 89.3

0.034

INR

1.7 ± 0.6

2.2 ± 0.9

<0.0001

Creatinine (mg/dl)

1.4 ± 1.9

3.2 ± 2.0

<0.0001

ESR (mm/h)

14.3 ± 5.7

20.2± 5.7

< 0.001

CRP (mg/l)

15.2 ± 6.81

46.6 ± 5.4

< 0.001

NLR

2.2 ± 0.7

5.5 ± 1.6

< 0.001

Na (mEq/l)

132.4 ± 6.1

123.7 ± 8.6

<0.0001

MAP (mmHg)

79.7 ± 9.8

70.4 ± 15.7

<0.0001

Total ICU stay (days)

10.8 ± 6.4

6.8 ± 4.8

<0.0001

Total hospital stay (days)

11.9 ± 7.5

12 ± 7.8

0.937

Child-Pugh score

10.4 ± 1.2

12.3 ± 1.2

<0.0001

MELD

13.3 ± 2.6

18.7 ± 3.6

<0.0001

CLIF-C OF score

8.6 ± 1.2

11.3 ± 1.7

<0.0001

CLIF-C ACLF score

42.8 ± 8.2

55.6 ± 8.0

<0.0001

CLIF-C AD score

56.0 ± 12.1

76.1 ± 11.0

<0.0001

CLIF-SOFA score

7.1 ± 1.1

9.3 ± 1.8

<0.0001

  1. ACLF Acute-on-chronic liver failure, AD Acute decompensation, ALP Alkaline phosphatase, ALT Alanine aminotransferase, AST Aspartate aminotransferase, BP Blood pressure, CLIF-C Chronic liver failure consortium, GGT Gamma-glutamyl transferase, ICU Intensive care unit, ESR Erythrocyte sedimentation rate, CRP C-reactive protein, NLR Neutrophil-lymphocyte ratio, MAP Mean arterial pressure, MELD Model for end-stage liver disease, Na Sodium, OF Organ failure, PaO2 Partial pressure of arterial oxygen, SOFA Sequential organ failure assessment, WBCs White blood cells