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Table 4 Univariate and multivariate regression analysis of variables associated with mortality

From: Predicting in-hospital mortality of cirrhotic patients hospitalized with hepatic encephalopathy

Variables

Univariate analysis

Multivariate analysis

p

OR (CI95%)

p

OR (CI95%)

Bilirubin

0.137

1.033 (0.990–1.079)

  

Albumin

< 0.001*

0.092 (0.042–0.202)

0.558

0.079 (0.019–0.326)

INR

< 0.001*

4.083 (1.953–8.536)

0.138

1.853 (0.199–17.239)

AST

0.065

1.006 (1.0–1.0)

  

ALT

0.473

1.003 (0.996–1.0)

  

Creatinine

0.008*

1.495 (1.109–2.015)

0.433

0.624 (0.192–2.030)

Na

< 0.001*

0.851 (0.805–0.900)

0.012*

0.799 (0.640–0.998)

K

0.927

0.986 (0.722–1.346)

  

Hb

0.508

0.950 (0.817–1.105)

  

WBC

0.221

1.026 (0.985–1.069)

  

PLT

0.866

0.999 (0.993–1.006)

  

Grade of HE (III and IV vs. II)

< 0.001*

2.942 (1.958–4.422)

0.015*

4.513 (1.888–10.789)

Episode of HE (recurrent vs. first episode)

0.041*

2.789 (1.043–7.456)

0.807

0.813 (0.155–4.265)

Hospital stay

0.015*

1.123 (1.023–1.233)

0.637

1.038 (0.890–1.211)

CTP score

< 0.001*

1.295 (1.097–1.530)

0.311

0.519 (0.310–0.867)

MELD score

< 0.001*

1.077 (1.037–1.118)

0.046*

1.168 (0.846–1.614)

MELD-Na

< 0.001*

1.140 (1.086–1.196)

0.023*

0.850 (0.570–1.268)

APACHE II score

0.001*

1.128 (1.046–1.216)

0.680

1.045 (0.848–1.288)

CLIF-SOFA score

< 0.001*

1.341 (1.205–1.493)

0.001*

1.142 (0.888–1.467)

  1. ALT alanine aminotransferase, AST aspartate aminotransferase, PLT platelets, INR international normalized ratio, WBC white blood cells, HE hepatic encephalopathy, CTP Child-Turcotte-Pugh, MELD Model for End-stage Liver Disease, Na sodium, K potassium, CLIF-SOFA Chronic Liver Failure-Sequential Organ Failure Assessment, APACHE II Acute Physiology and Chronic Health Evaluation II, OR odds ratio, CI confidence interval
  2. *Statistically significant value