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Table 4 Univariate and multivariate regression analysis of variables associated with mortality

From: Predicting in-hospital mortality of cirrhotic patients hospitalized with hepatic encephalopathy

Variables Univariate analysis Multivariate analysis
p OR (CI95%) p OR (CI95%)
Bilirubin 0.137 1.033 (0.990–1.079)   
Albumin < 0.001* 0.092 (0.042–0.202) 0.558 0.079 (0.019–0.326)
INR < 0.001* 4.083 (1.953–8.536) 0.138 1.853 (0.199–17.239)
AST 0.065 1.006 (1.0–1.0)   
ALT 0.473 1.003 (0.996–1.0)   
Creatinine 0.008* 1.495 (1.109–2.015) 0.433 0.624 (0.192–2.030)
Na < 0.001* 0.851 (0.805–0.900) 0.012* 0.799 (0.640–0.998)
K 0.927 0.986 (0.722–1.346)   
Hb 0.508 0.950 (0.817–1.105)   
WBC 0.221 1.026 (0.985–1.069)   
PLT 0.866 0.999 (0.993–1.006)   
Grade of HE (III and IV vs. II) < 0.001* 2.942 (1.958–4.422) 0.015* 4.513 (1.888–10.789)
Episode of HE (recurrent vs. first episode) 0.041* 2.789 (1.043–7.456) 0.807 0.813 (0.155–4.265)
Hospital stay 0.015* 1.123 (1.023–1.233) 0.637 1.038 (0.890–1.211)
CTP score < 0.001* 1.295 (1.097–1.530) 0.311 0.519 (0.310–0.867)
MELD score < 0.001* 1.077 (1.037–1.118) 0.046* 1.168 (0.846–1.614)
MELD-Na < 0.001* 1.140 (1.086–1.196) 0.023* 0.850 (0.570–1.268)
APACHE II score 0.001* 1.128 (1.046–1.216) 0.680 1.045 (0.848–1.288)
CLIF-SOFA score < 0.001* 1.341 (1.205–1.493) 0.001* 1.142 (0.888–1.467)
  1. ALT alanine aminotransferase, AST aspartate aminotransferase, PLT platelets, INR international normalized ratio, WBC white blood cells, HE hepatic encephalopathy, CTP Child-Turcotte-Pugh, MELD Model for End-stage Liver Disease, Na sodium, K potassium, CLIF-SOFA Chronic Liver Failure-Sequential Organ Failure Assessment, APACHE II Acute Physiology and Chronic Health Evaluation II, OR odds ratio, CI confidence interval
  2. *Statistically significant value