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Table 3 Osler-Weber-Rendu disease monitoring [6]

From: Ischemic cholangitis during Osler-Weber-Rendu disease: a case report

Test

Surveillance

Physical exam

Annual, to detect new symptoms

Testing for occult blood in stool

Annual, to detect occult gastrointestinal bleeding

Complete blood count

Annual, to detect new-onset anemia

Pulse oximetry in the supine and sitting

Every 1–2 years during childhood, to screen for pulmonary AVM

Contrast echocardiogram

For patients aged 10 years and older, to screen for pulmonary shuntting

Chest CT scan (existing pulmonary AVM)

Every 3–5 years, to reassess the growth of vascular lesions and to exclude the presence of new pulmonary

Arterial blood gases or a chest CT, or both

1 year after embolization to exclude reperfusion of previously treated pulmonary AVM

Liver screening for arteriovenous malformation

No need to be routinely performed

Cerebral MRI

Once after the diagnosis to exclude cerebral AVM