Study of the effect of vascular endothelial growth factor (VEGF) C(+405)G (rs2010963) single nucleotide polymorphism on the development of esophageal and gastric varices and risk of variceal bleeding in cirrhotic hepatitis C virus (HCV) patients (VEGF) C(+405)G IN esophageal and gastric varices

Egyptian Liver Journal

Table 5 Relation between (VEGF) C(+405)G (rs2010963) SNP with grade of esophageal varices, risk signs of variceal bleeding, gastric varices, and variceal bleeding in group A

	VEGF gene						^MCp
	CC (n = 7)		CG (n = 10)		GG (n = 13)
	No.	%	No.	%	No.	%
Grade of esophageal varices
I	4	57.1	2	20.0	0	0.0	< 0.001*
II	2	28.6	3	30.0	0	0.0
III	1	14.3	2	20.0	1	7.7
IV	0	0.0	3	30.0	12	92.3
Risk signs of variceal bleeding
No	4	57.1	4	40.0	0	0.0	MCp = 0.004*
Yes	3	42.9	6	60.0	13	100.0
Gastric varices
No	7	100.0	8	80.0	4	30.8	0.003*
Yes	0	0.0	2	20.0	9	69.2	0.003*
Variceal bleeding
No	5	71.4	7	70.0	2	15.4	0.009*
Yes	2	28.6	3	30.0	11	84.6

χ² Chi square test, MC Monte Carlo, p p value for comparing between different categories
*Statistically significant at p ≤ 0.05