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Table 4 VEGF C(+405)G (rs2010963) SNP genotype and risk for esophageal varices

From: Study of the effect of vascular endothelial growth factor (VEGF) C(+405)G (rs2010963) single nucleotide polymorphism on the development of esophageal and gastric varices and risk of variceal bleeding in cirrhotic hepatitis C virus (HCV) patients (VEGF) C(+405)G IN esophageal and gastric varices

 

Group (n = 30)

Group B (n = 30)

p

OR (95% C.I.)

No.

%

No.

%

VEGF genotype

 CC

7

23.3

16

53.3

 

1.000

 CG

10

33.3

12

40.0

0.301

1.905 (0.561‑6.464)

 GG

13

43.3

2

6.7

0.002*

14.857 (2.625‑84.100)

Allele

 C

24

40.0

44

73.3

 

1.000

 G

36

60.0

16

26.7

< 0.001*

4.125 (1.908‑8.916)

  1. Group A, cirrhosis with esophageal varices
  2. Group B, cirrhosis without esophageal varices
  3. OR odd’s ratio, C.I. confidence interval, LL lower limit, UL upper limit
  4. *Statistically significant at p ≤ 0.05n