Validity of serum leukotriene B4 as a marker of decompensated liver cirrhosis in chronic HCV patients: leukotriene B4 in decompensated liver cirrhosis

Egyptian Liver Journal

Table 2 Agreement (sensitivity, specificity) for LTB4 to diagnose decompensated cirrhosis group (n = 30) from compensated cirrhosis group (n = 30)

	AUC	P	95% C.I	Cut off^a	Sensitivity %	Specificity %	PPV %	NPV %	Accuracy of the test %
Serum leukotriene B4	0.728	0.002^*	0.601–0.855	> 16.2	93.33	43.33	62.2	86.7	66.7

AUC Area under a curve, p value Probability value, CI Confidence Intervals, NPV Negative predictive value, PPV Positive predictive value
*Statistically significant at p ≤ 0.05
^aCutoff was chosen according to the Youden index