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Table 1 Sensitivity and specificity of HCV Ag in predicted HCV RNA in 109 anti-HCV positive patients

From: Role of hepatitis C virus core antigen assay in hepatitis C care in developing country

   HCV RNA
   Positive Negative Total
HCV Ag Positive 96 0 96
Negative 5 8 13
Total 101 8 109
  1. HCV Ag negative: HCV Ag < 3 fmol/L; HCV RNA negative: HCV RNA < 15 IU/mL
  2. Sensitivity = 96/101 = 95.05%
  3. Specificity = 8/8 = 100%
  4. Positive predictive value (PPV) = 96/96 = 100%
  5. Negative predictive value (NPV) = 8/13 = 61.54%