From: Role of serum Nogo-B as a biomarker for diagnosis of chronic liver diseases and its severity
Variables | Group І (n = 24) | Group II (n = 24) | Group III (n = 24) | Control (n = 18) | P1 | P2 | |
---|---|---|---|---|---|---|---|
Hematemesis and melena | 21 | 15 | 6 | ||||
Bleeding tendency | 2 | 4 | 7 | ||||
Hepatic encephalopathy | 0 | 2 | 8 | ||||
Jaundice | 0 | 5 | 17 | ||||
Ultrasound findings | Hepatomegaly | 20 | 21 | 6 | |||
Liver cirrhosis | 19 | 24 | 24 | ||||
Splenomegaly | 20 | 23 | 23 | ||||
Ascites | 3 | 21 | 24 | ||||
Varices (upper GI endoscopy) | 18 | 24 | 24 | ||||
HB | 8.36 ± 2.26 | 8.09 ± 1.48 | 9.04 ± 2.17 | 12.49 ± 1.98 | < 0.001 | 0.338 | |
PLT | 122.75 ± 89.33 | 113.00 ± 70.54 | 103.75 ± 62.60 | 302.00 ± 63.24 | < 0.001 | 0.850 | |
Urea | 45.46 ± 28.14 | 57.67 ± 30.67 | 56.54 ± 24.23 | 30.44 ± 5.76 | < 0.001 | 0.159 | |
Creatinine | 0.91 ± 0.32 | 1.05 ± 0.25 | 1.26 ± 0.41 | 1.02 ± 0.17 | 0.800 | 0.004 | |
Na | 138.04 ± 3.09 | 136.46 ± 3.66 | 134.96 ± 5.86 | 139.83 ± 3.54 | 0.004 | 0.045 | |
ALT | 30.25 ± 35.15 | 32.54 ± 17.18 | 60.87 ± 58.49 | 23.06 ± 7.30 | 0.048 | < 0.001 | |
AST | 41.12 ± 31.01 | 51.88 ± 28.04 | 100.63 ± 93.31 | 24.11 ± 7.31 | < 0.001 | < 0.001 | |
Alb | 3.28 ± 0.46 | 2.75 ± 0.30 | 2.21 ± 0.43 | 4.93 ± 0.57 | < 0.001 | < 0.001 | |
Bil | .89 ± 0.43 | 1.43 ± 0.66 | 3.37 ± 2.21 | 0.96 ± 0.17 | 0.026 | < 0.001 | |
PC | 69.92 ± 10.34 | 59.12 ± 11.98 | 47.67 ± 14.47 | 91.28 ± 7.34 | < 0.001 | < 0.001 | |
Ferritin | 61.52 ± 129.04 | 45.06 ± 60.87 | 44.48 ± 54.71 | 25.80 ± 19.45 | 0.525 | 0.882 | |
Positive anti-bilharzial ab | 12 | 17 | 11 |