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Egyptian Liver Journal
Fig. 2 | Egyptian Liver Journal

Fig. 2

From: Congenital hepatic fibrosis with novel mutations in PKD1 gene masquerading as early cryptogenic cirrhosis: a rare case report

Fig. 2

Sections from the wedge biopsy of liver showing a loss of normal architecture with irregular bridging fibrosis (black arrows) separating the liver parenchyma into lobules (white arrow) and irregular nodules (white arrow heads) (H&E, × 40). b Bile ductular proliferation (yellow arrow) and bile plugging (green arrow) (H&E, × 200). c Reticulin stain has highlighted the fibrosis (blue arrow) outlining a nodule and the nodule shows maintained reticulin framework (red arrow) (reticulin stain, × 100). d Masson’s trichrome stain has highlighted the irregular fibrosis (black arrow) between islands of liver parenchyma imparting a jigsaw-puzzle pattern (MT, × 40)

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