Reversion to regular diet with alternate day fasting can cure grade-I non-alcoholic fatty liver disease (NAFLD) in high-fructose-intake-associated metabolic syndrome

Gamil, Nehal Mohamed Bahgat; El Agaty, Sahar Mohamed; Megahed, Gehan Khalaf; Mansour, Rania Salah; Abdel-Latif, Marwa Saad

doi:10.1186/s43066-021-00128-1

Egyptian Liver Journal

Table 2 The 8th week and final anthropometric and lipid parameters in the five study groups

From: Reversion to regular diet with alternate day fasting can cure grade-I non-alcoholic fatty liver disease (NAFLD) in high-fructose-intake-associated metabolic syndrome

	BW (gm)		BMI (gm/cm²)		WC (cm)		TGs (mg/dl)		HDL-C (mg/dl)
	8^th week	Final	8^th week	Final	8^th week	Final	8^th week	Final	8^th week	Final
C	186.80 ±7.93 (10)	197.20 ±8.06 (10)	0.48 ±0.01 (10)	0.47 ±0.01 (10)	11.90 ±0.19 (10)	12.90* ±0.41 (10)	122.22 ±3.35 (9)	83.11* ±3.93 (9)	38.38 ±2.40 (8)	57.88* ±1.66 (8)
MS	183.50 ±5.97 (14)	194.50 ±7.77 (14)	0.49 ±0.02 (14)	0.48 ±0.02 (14)	11.96 ±0.18 (14)	12.93* ±0.30 (14)	116.10 ±8.28 (10)	136.30* ±4.70 (10)	27.50 ±3.69 (10)	27.40 ±1.55 (10)
MSRD	181.58 ±7.20 (12)	198.00* ±8.26 (12)	0.48 ±0.01 (12)	0.49 ±0.01 (12)	12.17 ±0.14 (12)	12.88* ±0.26 (12)	118.67 ±6.53 (9)	107.56 ±3.22 (9)	34.78 ±2.74 (9)	45.11* ±1.62 (9)
MSF	176.85 ±4.65 (13)	151.31* ±5.59 (13)	0.48 ±0.01 (13)	0.41* ±0.01 (13)	12.35 ±0.17 (13)	11.46* ±0.23 (13)	121.11 ±4.43 (9)	103.22* ±3.67 (9)	31.22 ±2.68 (9)	48.22* ±2.60 (9)
MSRDF	172.08 ±7.18 (12)	148.92* ±5.85 (12)	0.50 ±0.02 (12)	0.42* ±0.01 (12)	12.54 ±0.21 (12)	11.17* ±0.20 (12)	114.75 ±7.32 (8)	96.25 ±3.24 (8)	31.00 ±2.90 (8)	50.25* ±2.46 (8)

C, control group, MS, untreated metabolic syndrome group, MSRD, metabolic syndrome group reverted to regular rat chow, MSF, metabolic syndrome group on alternate day fasting, MSRDF, metabolic syndrome group reverted to regular rat chow and on alternate day fasting;
BW, body weight; BMI, body mass index; WC, waist circumference; TGs, triglycerides; HDL-C, high density lipoprotein cholesterol
In the parenthesis is the number of observations
Data are expressed as mean ± SEM
*: Significance from 8^th week value, by Student's “t” test for paired data, at P ≤0.05

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