Table 7 C/D ratio in correlation with different genotype of donor when recipient genotype is CC (Mann–Whitney test)

1st wk

 C/D ratio

Median (IQR)

44.1(34.5–70)

113(74–173.5)

−2.268

0.023

S

Range

32–75.2

48–221

 Dose

Median (IQR)

0.07(0.05–0.09)

0.07(0.02–0.4)

0.000

1.000

NS

Range

0.05–0.1

0.01–0.7

 Trough level

Median (IQR)

4.14(2.4–4.4)

3.55(1.4–6.05)

−0.189

0.850

NS

Range

1.6–4.9

1–6.8

2nd wk

 C/D

Median (IQR)

92.5(66.3–122.4)

65.45(55.25–94.33)

−1.323

0.186

NS

Range

66–170

54.5–113.75

 Dose

Median (IQR)

0.06(0.04–0.08)

0.08(0.06–2.05)

−1.245

0.213

NS

Range

0.03–0.08

0.05–4

 Trough level

Median (IQR)

4.2(3.7–8.4)

4.78(3.63–5.3)

−0.379

0.705

NS

Range

3.7–8.5

2.8–5.5

3rd wk

 C/D

Median (IQR)

78(53.6–112)

125.3(82.5–157.3)

−1.136

0.256

NS

Range

38.16–116

60–169

 Dose

Median (IQR)

0.06(0.04–0.09)

0.07(0.04–2.64)

−0.190

0.849

NS

Range

0.02–0.1

0.02–5.2

 Trough level

Median (IQR)

5.2(3.6–6.5)

5.2(3.88–8.1)

0.000

1.000

NS

Range

3.3–9

3.16–10.4

4th wk

 C/D

Median (IQR)

99.5(63–141)

107.35(85.1–285.75)

−0.756

0.450

NS

Range

62.1–167

79–448

 Dose

Median (IQR)

0.05(0.04–0.09)

0.04(0.02–2.28)

−0.579

0.563

NS

Range

0.04–0.2

0.02–4.5

 Trough level

Median (IQR)

5.85(5.2–6.5)

3.51(2.13–5.14)

−1.492

0.136

NS

Range

3–7.75

1.4–6.1

2 months

 Dose

Median (IQR)

0.1(0.04–0.1)

0.09(0.07–0.1)

−0.232

0.817

NS

Range

0.04–0.1

0.07–0.1

 Trough level

Median (IQR)

5.9(2.9–10.6)

4.7(3.8–12.9)

−0.218

0.827

NS

Range

2.9–10.6

3.8–12.9

 C/D

Median (IQR)

73(49–106)

54(47–143)

−0.218

0.827

NS

Range

49–106

47–143

3 months

 Dose

Median (IQR)

0.05(0.02–0.07)

0.09(0.08–0.1)

−1.964

0.050

NS

Range

0.02–0.07

0.08–0.1

 Trough level

Median (IQR)

5(4.5–8.8)

4.9(3.2–7.4)

−0.655

0.513

NS

Range

4.5–8.8

3.2–7.4

 C/D

Median (IQR)

176(71–225)

61(32–82)

−1.528

0.127

NS

Range

71–225

32–82