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Table 1 Descriptive statistics of demographic, clinical, endoscopic and histopathological parameters of the studied cases (N = 86)

From: Prevalence of esophageal eosinophilia in patients referred for diagnostic upper gastrointestinal endoscopy

Variable

N

%

Residence:

rural

62

72.1

urban

24

27.9

Heart burn

84

97.7

Upper abdominal pain

78

90.7

Nausea

42

48.8

Vomiting

24

27.9

Dysphagia

22

25.6

Unintentional weight loss

5

5.8

Current smoking

14

16.3

Atopy

8

9.3

DM

4

4.7

Hypertension

10

11.6

NSAIDs use

8

9.3

PPI use

76

88.4

PPI duration (months) median (min.-max.)

3

(0-12)

Reflux oesophagitis

16

18.6

Grade A

10

11.6

Grade B

4

4.7

Grade C

2

2.3

Incompetent cardia

42

48.8

Hiatus hernia

8

9.3

Fixed rings (Trachealization)

6

7

Gastritis

59

68.6

Antral gastritis

45

52.3

Pan gastritis

14

16.3

Histopathologically Oesophagitis

46

53.5

Mild

32

37.2

Severe

14

16.3

Eosinophilic oesophagitis (eosinophils ≥ 15/HPF)

3

3.5

Basal cell hyperplasia

<  15%

48

55.8

15-30%

34

39.5

> 30%

4

4.7

Papillary elongation

< 50%

70

81.4

50-75%

16

18.6

Dilated intercellular space

Absent

36

41.9

< one lymphocyte diameter

40

46.5

≥ one lymphocyte diameter

10

11.6

Intraepithelial eosinophils

Absent

60

69.8

1-2 cells

20

23.3

  >  2 cells

6

7

Intraepithelial neutrophils

Absent

82

95.3

1-2 cells

2

2.3

>  2 cells

2

2.3

Intraepithelial mononuclear cells

0-9 cells

86

100

Chronic gastritis

70

81.4

H. pylori-associated gastritis

42

48.8

Descriptive statistics of clinico-demographic, laboratory, endoscopic and histopathological parameters the three eosinophilic oesophagitis cases (EoE) (N = 3)

Characteristic

Statistic

Sex

All were male patients

Age range

34-73 years

Current smoking

1 (33.3%)

DM, hypertension and atopy

None

NSAIDs use

None

PPI use (Duration range in months)

All (2-4 months)

Dysphagia

All

Upper abdominal pain and heart burn

All

Nausea and vomiting

None

Unintentional weight loss

None

WBC count range

5.8-6.3

Eosinophil count range

0.05-0.1

Eosinophilia

Mild eosinophilia in 1 case

Hemoglobin level range

13.3-14.0

Platelet count range

172-285

Hiatus hernia and incompetent cardia

1 (33.3%)

Fixed rings

2 (66.7%)

Reflux oesophagitis (ERD)

None

Basal cell hyperplasia

Present (15-30% of total thickness)

Papillary elongation

Normal (< 50%) in all

Dilated intercellular space

Dilated (<  1 lymphocyte) in all

Intra epithelial eosinophils

≥15/HPF in all

Intra epithelial neutrophils

> 2 cells in 1 patient

No cells in the two other patients

Intra epithelial mononuclear cells

Not present

reflux oesophagitis (histologically)

Severe reflux esophagitis in 1 patient.

No reflux in 2 other patients

H. pylori-associated chronic gastritis

All