Skip to main content

Table 1 Descriptive statistics of demographic, clinical, endoscopic and histopathological parameters of the studied cases (N = 86)

From: Prevalence of esophageal eosinophilia in patients referred for diagnostic upper gastrointestinal endoscopy

Variable N %
Residence:
rural 62 72.1
urban 24 27.9
Heart burn 84 97.7
Upper abdominal pain 78 90.7
Nausea 42 48.8
Vomiting 24 27.9
Dysphagia 22 25.6
Unintentional weight loss 5 5.8
Current smoking 14 16.3
Atopy 8 9.3
DM 4 4.7
Hypertension 10 11.6
NSAIDs use 8 9.3
PPI use 76 88.4
PPI duration (months) median (min.-max.) 3 (0-12)
Reflux oesophagitis 16 18.6
Grade A 10 11.6
Grade B 4 4.7
Grade C 2 2.3
Incompetent cardia 42 48.8
Hiatus hernia 8 9.3
Fixed rings (Trachealization) 6 7
Gastritis 59 68.6
Antral gastritis 45 52.3
Pan gastritis 14 16.3
Histopathologically Oesophagitis 46 53.5
Mild 32 37.2
Severe 14 16.3
Eosinophilic oesophagitis (eosinophils ≥ 15/HPF) 3 3.5
Basal cell hyperplasia
<  15% 48 55.8
15-30% 34 39.5
> 30% 4 4.7
Papillary elongation
< 50% 70 81.4
50-75% 16 18.6
Dilated intercellular space
Absent 36 41.9
< one lymphocyte diameter 40 46.5
≥ one lymphocyte diameter 10 11.6
Intraepithelial eosinophils
Absent 60 69.8
1-2 cells 20 23.3
  >  2 cells 6 7
Intraepithelial neutrophils
Absent 82 95.3
1-2 cells 2 2.3
>  2 cells 2 2.3
Intraepithelial mononuclear cells
0-9 cells 86 100
Chronic gastritis 70 81.4
H. pylori-associated gastritis 42 48.8
Descriptive statistics of clinico-demographic, laboratory, endoscopic and histopathological parameters the three eosinophilic oesophagitis cases (EoE) (N = 3)
Characteristic Statistic
Sex All were male patients
Age range 34-73 years
Current smoking 1 (33.3%)
DM, hypertension and atopy None
NSAIDs use None
PPI use (Duration range in months) All (2-4 months)
Dysphagia All
Upper abdominal pain and heart burn All
Nausea and vomiting None
Unintentional weight loss None
WBC count range 5.8-6.3
Eosinophil count range 0.05-0.1
Eosinophilia Mild eosinophilia in 1 case
Hemoglobin level range 13.3-14.0
Platelet count range 172-285
Hiatus hernia and incompetent cardia 1 (33.3%)
Fixed rings 2 (66.7%)
Reflux oesophagitis (ERD) None
Basal cell hyperplasia Present (15-30% of total thickness)
Papillary elongation Normal (< 50%) in all
Dilated intercellular space Dilated (<  1 lymphocyte) in all
Intra epithelial eosinophils ≥15/HPF in all
Intra epithelial neutrophils > 2 cells in 1 patient
No cells in the two other patients
Intra epithelial mononuclear cells Not present
reflux oesophagitis (histologically) Severe reflux esophagitis in 1 patient.
No reflux in 2 other patients
H. pylori-associated chronic gastritis All