Table 1 Descriptive statistics of demographic, clinical, endoscopic and histopathological parameters of the studied cases (N = 86)
Variable | N | % |
Residence: | ||
 rural | 62 | 72.1 |
 urban | 24 | 27.9 |
Heart burn | 84 | 97.7 |
Upper abdominal pain | 78 | 90.7 |
Nausea | 42 | 48.8 |
Vomiting | 24 | 27.9 |
Dysphagia | 22 | 25.6 |
Unintentional weight loss | 5 | 5.8 |
Current smoking | 14 | 16.3 |
Atopy | 8 | 9.3 |
DM | 4 | 4.7 |
Hypertension | 10 | 11.6 |
NSAIDs use | 8 | 9.3 |
PPI use | 76 | 88.4 |
PPI duration (months) median (min.-max.) | 3 | (0-12) |
Reflux oesophagitis | 16 | 18.6 |
 Grade A | 10 | 11.6 |
 Grade B | 4 | 4.7 |
 Grade C | 2 | 2.3 |
Incompetent cardia | 42 | 48.8 |
Hiatus hernia | 8 | 9.3 |
Fixed rings (Trachealization) | 6 | 7 |
Gastritis | 59 | 68.6 |
 Antral gastritis | 45 | 52.3 |
 Pan gastritis | 14 | 16.3 |
Histopathologically Oesophagitis | 46 | 53.5 |
 Mild | 32 | 37.2 |
 Severe | 14 | 16.3 |
Eosinophilic oesophagitis (eosinophils ≥ 15/HPF) | 3 | 3.5 |
Basal cell hyperplasia | ||
 <  15% | 48 | 55.8 |
 15-30% | 34 | 39.5 |
 > 30% | 4 | 4.7 |
Papillary elongation | ||
 < 50% | 70 | 81.4 |
 50-75% | 16 | 18.6 |
Dilated intercellular space | ||
 Absent | 36 | 41.9 |
 < one lymphocyte diameter | 40 | 46.5 |
 ≥ one lymphocyte diameter | 10 | 11.6 |
Intraepithelial eosinophils | ||
 Absent | 60 | 69.8 |
 1-2 cells | 20 | 23.3 |
  >  2 cells | 6 | 7 |
Intraepithelial neutrophils | ||
 Absent | 82 | 95.3 |
 1-2 cells | 2 | 2.3 |
 >  2 cells | 2 | 2.3 |
Intraepithelial mononuclear cells | ||
 0-9 cells | 86 | 100 |
Chronic gastritis | 70 | 81.4 |
H. pylori-associated gastritis | 42 | 48.8 |
Descriptive statistics of clinico-demographic, laboratory, endoscopic and histopathological parameters the three eosinophilic oesophagitis cases (EoE) (N = 3) | ||
Characteristic | Statistic | |
Sex | All were male patients | |
Age range | 34-73 years | |
Current smoking | 1 (33.3%) | |
DM, hypertension and atopy | None | |
NSAIDs use | None | |
PPI use (Duration range in months) | All (2-4 months) | |
Dysphagia | All | |
Upper abdominal pain and heart burn | All | |
Nausea and vomiting | None | |
Unintentional weight loss | None | |
WBC count range | 5.8-6.3 | |
Eosinophil count range | 0.05-0.1 | |
Eosinophilia | Mild eosinophilia in 1 case | |
Hemoglobin level range | 13.3-14.0 | |
Platelet count range | 172-285 | |
Hiatus hernia and incompetent cardia | 1 (33.3%) | |
Fixed rings | 2 (66.7%) | |
Reflux oesophagitis (ERD) | None | |
Basal cell hyperplasia | Present (15-30% of total thickness) | |
Papillary elongation | Normal (< 50%) in all | |
Dilated intercellular space | Dilated (<  1 lymphocyte) in all | |
Intra epithelial eosinophils | ≥15/HPF in all | |
Intra epithelial neutrophils | > 2 cells in 1 patient No cells in the two other patients | |
Intra epithelial mononuclear cells | Not present | |
reflux oesophagitis (histologically) | Severe reflux esophagitis in 1 patient. No reflux in 2 other patients | |
H. pylori-associated chronic gastritis | All | |