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Table 2 Sensitivity, specificity, positive, and negative predictive values of AFP and CK 19 in studied patients

From: Serum level of cytokeratin 19 as a diagnostic and prognostic marker in patients with HCV-related hepatocellular carcinoma

 

Best cutoff

SN

SP

PPV

NPV

AFP

25.5 ng/ml

80.5%

75%

93%

48.4%

CK 19

6.25 ng/ml

63.4%

55%

85.2%

26.8%

Combined AFP and CK 19

25.5 ng/ml and 6.25 ng/ml

93.9%

45%

87.5%

64.3%

  1. AFP alpha-fetoprotein, CK 19 cytokeratin 19, SN sensitivity, SP specificity, PPV positive predictive value, NPV negative predictive value