Table 1 Baseline characteristics of the study population
|  | The whole group | NAS < 4 (n = 31) | NAS ≥ 4 (n = 66) | P value | |
|---|---|---|---|---|---|
Age | 42.02 (8.99) | 42 (10.44) | 42.03 (8.30) | 0.9 | |
Gender Male/female | 25 (25.8%)/72 (74.2%) | 10 (32.2%)/21(67.7%) | 15 (22.72%)/51 (77.27%) | 0.3 | |
Residence Rural/urban | 18 (27.3%)/48 (72.7%) | 4 (12.9%)/16 (51.61%) | 14 (21.21%)/32 (48.48%) | 0.4 | |
Diabetes mellitus | 20 (20.6%) | 2 (6.45%) | 18 (27.27%) | 0.01 | |
Hypertension | 13 (13.40%) | 2 (6.45%) | 11 (16.67%) | 0.1 | |
BMI median (IQR) | 32.9 (29.15-38.14) | 32 (28-35.99) | 33.05 (30-38.86) | 0.2 | |
Waist circumference | Males Median (IQR) | 55 (16.84%) | 44 (40-50) | 52 (49-62) | 0.07 |
Females Median (IQR) | 81 (38.41%) | 48.5 (45-56) | 68 (55-127) | 0.01 | |
Laboratory parameters | Â | ||||
Hemoglobin | 12.91 (1.70) | 12.61 (2.08) | 13.05 (1.49) | 0.2 | |
Platelets | 272.12 (69.69) | 272.97 (62.003) | 271.72 (73.52) | 0.9 | |
AST median (IQR) | 30 (22-41.5) | 27 (22-34) | 30 (23-44) | 0.06 | |
ALT median (IQR) | 32.5 (21-57) | 26 (18-38) | 40 (23-60) | 0.01 | |
Bilirubin median (IQR) | 0.56 (0.4-0.9) | 0.5 (0.4-0.84) | 0.6 (0.4-0.9) | 0.8 | |
Albumin | 4.27 (0.43) | 4.21 (0.48) | 4.30 (0.41) | 0.4 | |
INR | 1.001 (0.09) | 1.01 (0.05) | 0.99 (0.10) | 0.7 | |
Cholesterol median (IQR) | 202 (177-229) | 202 (166-225) | 202 (180-234) | 0.4 | |
Triglycerides median (IQR) | 140 (100-180) | 141 (96-200) | 135.5 (100-179.5) | 0.9 | |
FBG median (IQR) | 99.5 (90-110) | 92 (86-101) | 100 (90-116) | 0.04 | |
Liver biopsy | Â | ||||
Type of steatosis | Macro and microvesicular | 29 (59.2%) | 10 | 19 | 0.3 |
Macrovesicular | 12 (24.5%) | 4 | 8 | ||
Microvesicular | 8 (16.3%) | 5 | 3 | ||
Fibrosis stage | F0 | 31 (31.96%) | 13 | 18 | 0.04 |
F1 | 46 (47.42%) | 17 | 29 | ||
F2 | 17 (17.5%) | 1 | 16 | ||
F3 | 2 (2.1%) | 0 | 2 | ||
F4 | 1 (1.03%) | 0 | 1 | ||