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Table 3 Liver histopathological scoring system showing number and frequency distribution (%) of each component examined in two different field sections in 10 rats (20 fields/group)

From: Hepatic ischemia reperfusion injury: effect of moderate intensity exercise and oxytocin compared to l-arginine in a rat model

Component

Congestiona

Vacuolizationa

Necrosis

Defined range Group

0

1

2

3

4

0

1

2

3

4

0

1

2

3

4

Sham-operated control group

16

3

1

0

0

19

1

0

0

0

18

2

0

0

0

80%

15%

5%

  

95%

5%

   

90%

10%

   

Hepatic ischemia-reperfusion group

2

2

3

13

0

3

1

5

11

0

1

4

11

4

0

10%

10%

15%

65%

 

15%

5%

25%

55%

 

5%

20%

55%

20%

 

l-arginine-treated hepatic ischemia-reperfusion group

2

3

4

11

0

2

10

5

3

0

4

9

4

3

0

10%

15%

20%

55%

 

10%

50%

25%

15%

 

20%

45%

20%

15%

 

Exercise-trained hepatic ischemia-reperfusion group

3

12

3

2

0

4

12

3

1

0

6

10

2

2

0

15%

60%

15%

10%

 

20%

60%

15%

5%

 

30%

50%

10%

10%

 

Oxytocin-treated hepatic ischemia-reperfusion group

2

4

4

10

0

2

10

4

4

0

4

11

3

2

0

10%

20%

20%

50%

 

10%

50%

20%

20%

 

20%

55%

15%

10%

 

Exercise-trained and oxytocin-treated hepatic ischemia-reperfusion group

3

3

11

3

0

3

12

3

2

0

6

11

2

1

0

15%

15%

55%

15%

 

15%

60%

15%

10%

 

30%

55%

10%

5%

 
  1. In component: necrosis, the defined ranges indicate; 0= No damage; 1=Single cell necrosis; 2= less than 30% necrosis; 3= less than 60% necrosis; 4= more than 60% necrosis
  2. aIn components: Congestion and vacuolization, the defined ranges indicate; 0= No damage; 1=Minimal congestion, minimal vacuolization; 2= Mild congestion, mild vacuolization; 3= Moderate congestion, moderate vacuolization; 4= Severe congestion, severe vacuolization