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Table 3 Liver histopathological scoring system showing number and frequency distribution (%) of each component examined in two different field sections in 10 rats (20 fields/group)

From: Hepatic ischemia reperfusion injury: effect of moderate intensity exercise and oxytocin compared to l-arginine in a rat model

Component Congestiona Vacuolizationa Necrosis
Defined range Group 0 1 2 3 4 0 1 2 3 4 0 1 2 3 4
Sham-operated control group 16 3 1 0 0 19 1 0 0 0 18 2 0 0 0
80% 15% 5%    95% 5%     90% 10%    
Hepatic ischemia-reperfusion group 2 2 3 13 0 3 1 5 11 0 1 4 11 4 0
10% 10% 15% 65%   15% 5% 25% 55%   5% 20% 55% 20%  
l-arginine-treated hepatic ischemia-reperfusion group 2 3 4 11 0 2 10 5 3 0 4 9 4 3 0
10% 15% 20% 55%   10% 50% 25% 15%   20% 45% 20% 15%  
Exercise-trained hepatic ischemia-reperfusion group 3 12 3 2 0 4 12 3 1 0 6 10 2 2 0
15% 60% 15% 10%   20% 60% 15% 5%   30% 50% 10% 10%  
Oxytocin-treated hepatic ischemia-reperfusion group 2 4 4 10 0 2 10 4 4 0 4 11 3 2 0
10% 20% 20% 50%   10% 50% 20% 20%   20% 55% 15% 10%  
Exercise-trained and oxytocin-treated hepatic ischemia-reperfusion group 3 3 11 3 0 3 12 3 2 0 6 11 2 1 0
15% 15% 55% 15%   15% 60% 15% 10%   30% 55% 10% 5%  
  1. In component: necrosis, the defined ranges indicate; 0= No damage; 1=Single cell necrosis; 2= less than 30% necrosis; 3= less than 60% necrosis; 4= more than 60% necrosis
  2. aIn components: Congestion and vacuolization, the defined ranges indicate; 0= No damage; 1=Minimal congestion, minimal vacuolization; 2= Mild congestion, mild vacuolization; 3= Moderate congestion, moderate vacuolization; 4= Severe congestion, severe vacuolization