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Table 1 Hematological, chemical profile, and viral load of HCV patients before and after DAA treatment

From: Effect of directly acting anti-viral agents on immunological imprints in chronic HCV-4a patients: interleukin-10 and vascular endothelial growth factor genes expression level

 

Before treatment

After treatment

p value

ALT (U/L)

Min–max

13–135

4–35

0.0003*

Mean

46.40

21.08

 

AST (U/L)

Min–max

8–124

16–35

0.0001*

Mean

43.96

21.96

 

Albumin (g/dl)

Min–max

2.8–5.2

3.5–4.8

0.3310

Mean

3.98

4.04

 

Total bilirubin (mg/dl)

Min–max

0.3–3.05

0.3–1.2

0.406

Mean

0.73

0.67

 

Direct bilirubin (mg/dl)

Min–max

0.1–2.14

0.1–0.6

0.155

Mean

0.35

0.26

 

Platelets count (× 103/μl)

Min–max

40–304

55–266

0.481

Mean

178.08

177.28

 

PT (INR)

Min–max

1–1.9

1–1.2

0.022*

Mean

1.18

1.08

 

HCV load (×105 IU/L)

Min–max

0.241–130

Undetectable

_

Mean

13.22

  
  1. *Statistically significant at p ≤ 0.05