IL-28B single nucleotide polymorphism as a predictor of hepatocellular carcinoma after treatment of chronic hepatitis C patients with direct acting antivirals

Egyptian Liver Journal

Table 6 Genotypes and alleles distribution among studied groups

Polymorphism	Control group N=100 (%)	Cirrhosis group N=50 (%)	HCC group N=50 (%)	Test of significance
TT	8 (8.0)	14 (28.0)	9 (18.0)	χ²=13.12	p1=0.004*
CC	28 (28.0)	10 (20.0)	7 (14.0)	p=0.01*	p2=0.054
CT	64 (64.0)	26 (52.0)	34 (68.0)		p3=0.26
HWE	0.008*	0.741	0.126
Allele	n=200	N=100	N=100		p1=0.02*
T	80 (40)	54 (54.0)	52 (52.0)	χ²=6.87	p2=0.051
C	120 (60)	46 (46.0)	48 (48.0)	p=0.03*	p3=0.77