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Table 1 Demographic, clinical, and biochemical properties of all classes

From: Annexin A5 as a marker for hepatocellular carcinoma in cirrhotic hepatitis C virus patients

Variables Cirrhosis with HCC group (n = 44) Cirrhosis without HCC group (n = 47) P1value Control group (n = 20) P value
Age (years) 57.7 ± 5.75 56.8 ± 6.89 0.968 (NS) 54.5(50.5–60.5) 0.337 (NS)
Sex (M/F) 23/21 27/20 0.751 (NS) 10/10 0.587 (NS)
MELD 16.1 ± 4.16 15.1 ± 4.57 0.568 (NS)
Child–Pugh class (A/B/C) 12/20/12 14/18/14 0.733 (NS)
ALT (U/L) 51 ± 17.65 53.3 ± 15.94 0.761 (NS) 11.9 ± 3.47 < 0.001* (HS)
AST(U/L) 69 ± 23.39 68.2 ± 19.51 0.944 (NS) 15.4 ± 4.83 < 0.001* (HS)
ALKP (U/L) 107.60 ± 37.05 114.40 ± 41.84 0.068 (NS) 48.6 ± 10.49 < 0.001* (HS)
GGT (mg/dl) 51.09 ± 37.75 48.94 ± 26.37 0.818 (NS) 14.6 ± 4.57 < 0.001* (HS)
INR 1.5 ± 0.47 1.59 ± 0.51 0.542 (NS) 1.005 ± 0.49 < 0.001* (HS)
PT(s) 17.51 ± 4.21 18.62 ± 4.64 0.533 (NS) 13.07 ± 0.18 < 0.001* (HS)
Total bilirubin (mg/dl) 2.55 ± 1.61 2.59 ± 2.01 0.579 (NS) 0.49 ± 0.25 < 0.001* (HS)
Albumin (g/dl) 2.97 ± 0.72 2.54 ± 0.79 0.098 (NS) 4.43 ± 0.59 < 0.001* (HS)
Platelet count (× 103/cm2) 113.04 ± 24.94 111.32 ± 17.63 0.935 (NS) 297.7 ± 17.87 < 0.001* (HS)
APRI score 1.88 ± 0.58 1.93 ± 0.61 0.794 (NS) 0.11 ± 0.03 < 0.001* (HS)
FIB-4 score 5.47 ± 1.04 5.32 ± 1.37 0.709 (NS) 0.57 ± 0.14 < 0.001* (HS)
Annexin A5 (ng/ml) 3.89 ± 0.85 3.06 ± 0.88 0.041 (S) 0.54 ± 0.11 < 0.001* (HS)
AFP (ng/ml) 270 ± 35 98 ± 20 < 0.001* (HS) 5.3 ± 2.9 < 0.001* (HS)